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Review
. 2022 Dec;43(23-24):2377-2391.
doi: 10.1002/elps.202200184. Epub 2022 Oct 17.

Taylor dispersion analysis of metallic-based nanoparticles - A short review

Jeremie Gouyon  1 , Ariane Boudier  1   2 , Fatima Barakat  1 , Arnaud Pallotta  1   2 , Igor Clarot  1   2
Affiliations
Free article
Review

Taylor dispersion analysis of metallic-based nanoparticles - A short review

Jeremie Gouyon et al. Electrophoresis. 2022 Dec.
Free article

Abstract

Taylor dispersion analysis (TDA) is an interesting tool for nanoparticle (NP) size determination, feasible using simple capillary electrophoresis apparatus. Based upon the radial diffusion of analytes upon a laminar stream, the diffusion coefficient of species is easily estimable. Moreover, TDA is generally more adequate than conventional dynamic light scattering methodologies as it is less dependent on the polydispersity of the sample, leading to accurate measurement and reliable results. This review provides every paper mentioning the use of TDA for metallic-based NPs size determination. Diverse strategies for the detection of metallic NPs (like UV-visible and inductively coupled plasma-mass spectrometry - ICP-MS - for instance) and interpretation of the Taylorgrams are discussed. Based upon the literature, advices on future prospects are also indicated, especially for the comparison of TDA results with other classical techniques.

Keywords: Taylor dispersion analysis; capillary; hydrodynamic radius; metallic nanoparticles; quality control.

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References

REFERENCES

    1. Zarschler K, Rocks L, Licciardello N, Boselli L, Polo E, Garcia KP, et al. Ultrasmall inorganic nanoparticles: state-of-the-art and perspectives for biomedical applications. Nanomed Nanotechnol Biol Med. 2016;12:1663-701.
    1. Pyell U, Jalil AH, Pfeiffer C, Pelaz B, Parak WJ. Characterization of gold nanoparticles with different hydrophilic coatings via capillary electrophoresis and Taylor dispersion analysis. Part I: Determination of the zeta potential employing a modified analytic approximation. J Colloid Interface Sci. 2015;450:288-300.
    1. Pan Y, Neuss S, Leifert A, Fischler M, Wen F, Simon U, et al. Size-dependent cytotoxicity of gold nanoparticles. Small. 2007;3:1941-9.
    1. Mourdikoudis S, Pallares RM, Thanh NTK. Characterization techniques for nanoparticles: comparison and complementarity upon studying nanoparticle properties. Nanoscale. 2018;10:12871-934.
    1. Fan Y, Marioli M, Zhang K. Analytical characterization of liposomes and other lipid nanoparticles for drug delivery. J Pharm Biomed Anal. 2021;192:113642.

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