Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct 20;11(10):e0075822.
doi: 10.1128/mra.00758-22. Epub 2022 Sep 26.

Complete Genome Sequences of Mycobacterium smegmatis Phages MelsMeow, Yorick, Virgeve, and Mikro

Victoria J Frost  1 , Jada E Fogle  1 , Ryan N Harris  1 , Brooke Jewell  1 , Kaylee E Mills  1 , Jessica E Morgan  1 , Precious T Thompson  1 , Emi Umemoto  1 , Kristi M Westover  1
Affiliations

Complete Genome Sequences of Mycobacterium smegmatis Phages MelsMeow, Yorick, Virgeve, and Mikro

Victoria J Frost et al. Microbiol Resour Announc. .

Abstract

Mycobacterium phages Mikro, Yorick, Virgeve, and MelsMeow were isolated from soil in Rock Hill, South Carolina. Mikro is a myovirus with a comparatively large genome of 157,166 bp. The remainder are siphoviruses with genome lengths ranging from 59,227 bp to 68,563 bp. All phages were isolated on Mycobacterium smegmatis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIG 1
FIG 1
Transmission electron micrographs of Mycobacterium phages MelsMeow (A), Yorick (B), Virgeve (C), and Mikro (D). Phage lysates were negatively stained with 1% uranyl acetate.
See this image and copyright information in PMC

References

    1. Dedrick RM, Smith BE, Cristinziano M, Freeman KG, Jacobs-Sera D, Belessis Y, Whitney Brown A, Cohen KA, Davidson RM, van Duin D, Gainey A, Garcia CB, Robert George CR, Haidar G, Ip W, Iredell J, Khatami A, Little JS, Malmivaara K, McMullan BJ, Michalik DE, Moscatelli A, Nick JA, Tupayachi Ortiz MG, Polenakovik HM, Robinson PD, Skurnik M, Solomon DA, Soothill J, Spencer H, Wark P, Worth A, Schooley RT, Benson CA, Hatfull GF. 2022. Phage therapy of Mycobacterium infections: compassionate-use of phages in twenty patients with drug-resistant mycobacterial disease. Clinical Infectious Diseases ciac453. doi:10.1093/cid/ciac453. - DOI - PMC - PubMed
    1. Nick JA, Dedrick RM, Gray AL, Vladar EK, Smith BE, Freeman KG, Malcolm KC, Epperson LE, Hasan NA, Hendrix J, Callahan K, Walton K, Vestal B, Wheeler E, Rysavy NM, Poch K, Caceres S, Lovell VK, Hisert KB, de Moura VC, Chatterjee D, De P, Weakly N, Martiniano SL, Lynch DA, Daley CL, Strong M, Jia F, Hatfull GF, Davidson RM. 2022. Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection. Cell 185:1860–1874.e12. doi:10.1016/j.cell.2022.04.024. - DOI - PMC - PubMed
    1. Gordon D, Green P. 2013. Consed: a graphical editor for next-generation sequencing. Bioinformatics 29:2936–2937. doi:10.1093/bioinformatics/btt515. - DOI - PMC - PubMed
    1. Miller JR, Koren S, Sutton G. 2010. Assembly algorithms for next-generation sequencing data. Genomics 95:315–327. doi:10.1016/j.ygeno.2010.03.001. - DOI - PMC - PubMed
    1. Russell DA, Hatfull GF. 2017. PhagesDB: the actinobacteriophage database. Bioinformatics 33:784–786. doi:10.1093/bioinformatics/btw711. - DOI - PMC - PubMed

LinkOut - more resources