Comment on

• Elucidation of CKAP4-remodeled cell mechanics in driving metastasis of bladder cancer through aptamer-based target discovery.

  Sun X, Xie L, Qiu S, Li H, Zhou Y, Zhang H, Zhang Y, Zhang L, Xie T, Chen Y, Zhang L, Zhao Z, Peng T, Liu J, Wu W, Zhang L, Li J, Ye M, Tan W. Sun X, et al. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2110500119. doi: 10.1073/pnas.2110500119. Epub 2022 Apr 11. Proc Natl Acad Sci U S A. 2022. PMID: 35412892 Free PMC article.
• TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease.

  Vickman RE, Aaron-Brooks L, Zhang R, Lanman NA, Lapin B, Gil V, Greenberg M, Sasaki T, Cresswell GM, Broman MM, Paez JS, Petkewicz J, Talaty P, Helfand BT, Glaser AP, Wang CH, Franco OE, Ratliff TL, Nastiuk KL, Crawford SE, Hayward SW. Vickman RE, et al. Nat Commun. 2022 Apr 19;13(1):2133. doi: 10.1038/s41467-022-29719-1. Nat Commun. 2022. PMID: 35440548 Free PMC article.
• HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.

  Lu X, Fong KW, Gritsina G, Wang F, Baca SC, Brea LT, Berchuck JE, Spisak S, Ross J, Morrissey C, Corey E, Chandel NS, Catalona WJ, Yang X, Freedman ML, Zhao JC, Yu J. Lu X, et al. Nat Genet. 2022 May;54(5):670-683. doi: 10.1038/s41588-022-01045-8. Epub 2022 Apr 25. Nat Genet. 2022. PMID: 35468964 Free PMC article.