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Review
. 2022 Oct;36(5):879-895.
doi: 10.1016/j.hoc.2022.07.002. Epub 2022 Sep 23.

Pancreatic Adenocarcinoma: Trends in Epidemiology, Risk Factors, and Outcomes

Elham Afghani  1 , Alison P Klein  2
Affiliations
Review

Pancreatic Adenocarcinoma: Trends in Epidemiology, Risk Factors, and Outcomes

Elham Afghani et al. Hematol Oncol Clin North Am. 2022 Oct.

Abstract

Pancreatic cancer is one of the most lethal cancers in the world; it is a silent disease in which symptoms do not present until advanced stages, thereby reducing the 5-year survival rate to 10%. The global burden of pancreatic cancer has doubled over the past 25 years despite advancements in medicine. This review aims to discuss the global trends and disparities in pancreatic cancer, as well as the up-to-date literature on the known risk factors. A better understanding of these risk factors will reduce mortality by providing opportunities to screen these patients as well as counseling on lifestyle modifications.

Keywords: Epidemiology; Pancreatic Adenocarcinoma; Pancreatic cancer; Risk Factors; Trend.

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Figures

Fig. 1.
Fig. 1.
Surveillance, Epidemiology and End Results (SEER) incidence rates by age at diagnosis, 2014 to 2018. (Adapted from SEER Database, National Cancer Institute. https://seer.cancer.gov/statfacts/html/pancreas.html Web site. Accessed December 18, 2021.)
Fig. 2.
Fig. 2.
Surveillance, Epidemiology and End Results (SEER) 5-year age-adjusted incidence rates, 2014 to 2018 by stage of diagnosis. (Adapted from SEER Database, National Cancer Institute. https://seer.cancer.gov/statfacts/html/pancreas.html Web site. Accessed December 18, 2021.)
Fig. 3.
Fig. 3.
Surveillance, Epidemiology and End Results (SEER) 5-year survival by stage of diagnosis, 2011 to 2017. (Adapted from SEER Database, National Cancer Institute. https://seer.cancer.gov/statfacts/html/pancreas.html Web site. Accessed December 18, 2021.)
See this image and copyright information in PMC

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