Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov;62(11):2405-2408.
doi: 10.1111/trf.17122. Epub 2022 Sep 26.

When should RhD-negative recipients be spared the transfusion of DEL red cells to avoid anti-D alloimmunization?

Hitoshi Ohto  1 , Willy Albert Flegel  2 , Hana Safic Stanic  3
Affiliations

When should RhD-negative recipients be spared the transfusion of DEL red cells to avoid anti-D alloimmunization?

Hitoshi Ohto et al. Transfusion. 2022 Nov.
No abstract available

Keywords: DEL; alloimmunization; anti-D; molecular typing; red cell genotyping.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest:

HO is a member of the “Department of Mesenchymal Stem Cell Research”, which is endowed by Alfresa Corporation. The other authors declare no conflict of interest.

Similar articles

See all similar articles

Cited by

References

    1. Seheult JN, Callum J, Delaney M, Drake R, Dunbar NM, Harm SK, et al. Rate of D-alloimmunization in trauma does not depend on the number of RhD-positive units transfused: The BEST collaborative study. Transfusion 2022. 10.1111/trf.16952 - DOI - PubMed
    1. Flegel WA, Wagner FF, Donghaile DPÓ. Anti-D immunization rates may exceed 50% in many clinically relevant settings, despite varying widely among patient cohorts. Transfusion 2020; 60:1109–10. - PMC - PubMed
    1. Yazer MH, Delaney M, Doughty H, Dunbar NM, Riyami AZ, Triulzi DJ, et al. It is time to reconsider the risks of transfusing RhD negative females of childbearing potential with RhD positive red blood cells in bleeding emergencies. Transfusion 2019; 59:3794–9. - PubMed
    1. Shao C-P. Transfusion of RhD-positive blood in “Asia Type” DEL recipients. N Engl J Med 2010; 362:472–473. - PubMed
    1. Flegel WA, von Zabern I, Wagner FF. Six years’ experience performing RHD genotyping to confirm D- red blood cell units in Germany for preventing anti-D immunizations. Transfusion 2009; 49:465–71. - PMC - PubMed

Publication types