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. 2022 Feb;52(1):105-112.
doi: 10.3906/sag-2109-84. Epub 2022 Feb 22.

Predictors of postendoscopic retrograde cholangiopancreatography associated cholangitis: a retrospective cohort study

Hasan Yılmaz  1 , Burcu Koçyiğit  2
Affiliations

Predictors of postendoscopic retrograde cholangiopancreatography associated cholangitis: a retrospective cohort study

Hasan Yılmaz et al. Turk J Med Sci. 2022 Feb.

Abstract

Background: Post-ERCP cholangitis (endoscopic retrograde cholangiopancreatography) and associated sepsis can be lifethreatening. Despite the wealth of studies on post-ERCP pancreatitis risk factors, there is limited data on post-ERCP cholangitis. This study aimed to investigate the rates, predictors, and outcomes of post-ERCP cholangitis.

Methods: A retrospective review of 452 ERCP cases performed by a single endoscopist at a tertiary center between March 2019 and February 2021 was performed. Patient-related, organizational and periprocedural factors that could affect post-ERCP cholangitis were evaluated. Predictors of post-ERCP cholangitis were determined by multivariable analysis.

Results: The post-ERCP cholangitis rate was 19.5%. Cholangiocarcinoma (OR 15.72, CI 2.43-101.55, p = 0.004), the American Society of Anesthesiologist Score (ASA) (OR 2.87, CI 1.14-7.21, p = 0.024), an increase in bilirubin after ERCP (OR 1.81 CI 1.01-3.22, p = 0.043), body mass index (OR 1.15, CI 1.00-1.33, p = 0.04) and procedure duration (OR 1.02, CI 1.00-1.05, p = 0.049) were predictors of post-ERCP cholangitis. Biliary stone extraction using a balloon was found to be protective against cholangitis (OR 0.18, CI 0.05-0.60, p = 0.005). Sepsis rate related to post-ERCP cholangitis was 2.4% and death 1%.

Keywords: ASA score; Post-ERCP cholangitis; malignant biliary obstruction; procedure duration.

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Conflict of interest statement

Conflict of interest

The authors have no conflicts of interest to declare that may have influenced either the conduct or the presentation of the research.

Figures

Figure
Figure
Flowchart of the study population.
See this image and copyright information in PMC

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