Persistent obstructive sleep apnoea in children: treatment options and management considerations
- PMID: 36162413
- DOI: 10.1016/S2213-2600(22)00262-4
Persistent obstructive sleep apnoea in children: treatment options and management considerations
Abstract
Unresolved obstructive sleep apnoea (OSA) after an adenotonsillectomy, henceforth referred to as persistent OSA, is increasingly recognised in children (2-18 years). Although associated with obesity, underlying medical complexity, and craniofacial disorders, persistent OSA also occurs in otherwise healthy children. Inadequate treatment of persistent OSA can lead to long-term adverse health outcomes beyond childhood. Positive airway pressure, used as a one-size-fits-all primary management strategy for persistent childhood OSA, is highly efficacious but has unacceptably low adherence rates. A pressing need exists for a broader, more effective management approach for persistent OSA in children. In this Personal View, we discuss the use and the need for evaluation of current and novel therapeutics, the role of shared decision-making models that consider patient preferences, and the importance of considering the social determinants of health in research and clinical practice. A multipronged, comprehensive approach to persistent OSA might achieve better clinical outcomes in childhood and promote health equity for all children.
Copyright © 2023 Elsevier Ltd. All rights reserved.
Conflict of interest statement
Declaration of interests SLI has a research grant from Inspire Medical. SR was partly supported by an Outstanding Investigator Award from the National Institutes of Health (NIH); she received consulting fees from Jazz Pharma, Eisai, Eli Lilly, and Apnimed; she serves on the scientific advisory board for Apnimed (Apnimed is developing pharmacological treatments for OSA in adult populations); and she received reimbursement for attending a meeting with an Eisai scientific advisory board in January, 2019. SR reports that her institution received loaned equipment for use in an NIH study from Philips Respironics and NOX Medical, and she is on the board for a non-profit patient advocacy group called Alliance for Sleep Apnea Partners. IN received consulting fees from Bayer. All other authors declare no competing interests.
Comment in
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Rapid maxillary expansion in paediatric obstructive sleep apnoea - Authors' reply.Lancet Respir Med. 2023 May;11(5):e46. doi: 10.1016/S2213-2600(23)00139-X. Epub 2023 Apr 17. Lancet Respir Med. 2023. PMID: 37080226 No abstract available.
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Rapid maxillary expansion in paediatric obstructive sleep apnoea.Lancet Respir Med. 2023 May;11(5):e45. doi: 10.1016/S2213-2600(23)00099-1. Epub 2023 Apr 17. Lancet Respir Med. 2023. PMID: 37080228 No abstract available.
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