Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Mar;11(3):283-296.
doi: 10.1016/S2213-2600(22)00262-4. Epub 2022 Sep 23.

Persistent obstructive sleep apnoea in children: treatment options and management considerations

Affiliations
Review

Persistent obstructive sleep apnoea in children: treatment options and management considerations

Refika Ersu et al. Lancet Respir Med. 2023 Mar.

Abstract

Unresolved obstructive sleep apnoea (OSA) after an adenotonsillectomy, henceforth referred to as persistent OSA, is increasingly recognised in children (2-18 years). Although associated with obesity, underlying medical complexity, and craniofacial disorders, persistent OSA also occurs in otherwise healthy children. Inadequate treatment of persistent OSA can lead to long-term adverse health outcomes beyond childhood. Positive airway pressure, used as a one-size-fits-all primary management strategy for persistent childhood OSA, is highly efficacious but has unacceptably low adherence rates. A pressing need exists for a broader, more effective management approach for persistent OSA in children. In this Personal View, we discuss the use and the need for evaluation of current and novel therapeutics, the role of shared decision-making models that consider patient preferences, and the importance of considering the social determinants of health in research and clinical practice. A multipronged, comprehensive approach to persistent OSA might achieve better clinical outcomes in childhood and promote health equity for all children.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests SLI has a research grant from Inspire Medical. SR was partly supported by an Outstanding Investigator Award from the National Institutes of Health (NIH); she received consulting fees from Jazz Pharma, Eisai, Eli Lilly, and Apnimed; she serves on the scientific advisory board for Apnimed (Apnimed is developing pharmacological treatments for OSA in adult populations); and she received reimbursement for attending a meeting with an Eisai scientific advisory board in January, 2019. SR reports that her institution received loaned equipment for use in an NIH study from Philips Respironics and NOX Medical, and she is on the board for a non-profit patient advocacy group called Alliance for Sleep Apnea Partners. IN received consulting fees from Bayer. All other authors declare no competing interests.

Comment in

LinkOut - more resources