Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 May-Jun;79(3):253-261.
doi: 10.1016/j.mjafi.2022.06.020. Epub 2022 Sep 22.

Management of COVID-19: A comprehensive and practical approach

M S Barthwal  1 , Sachinkumar Dole  2 , Tushar Sahasrabudhe  2
Affiliations
Review

Management of COVID-19: A comprehensive and practical approach

M S Barthwal et al. Med J Armed Forces India. 2023 May-Jun.

Abstract

Since the beginning of Corona Virus Disease (COVID) pandemic, there has been lack of clarity about the management protocols in spite of frequently updated national and international guidelines. Irrational use of unproven therapies has not been helpful in improving treatment outcomes. Early use of high-dose steroids or late use of antiviral medicines might have caused more harm than the benefit. There is also lot of fear about post-COVID fibrosis leading to extended use of steroids and antifibrotics. We reviewed the available COVID guidelines and treatment protocols in the light of scientific evidence generated over last 2 years by a systematic literature search using various databases (PubMed, Google Scholar, MEDLINE, UpToDate, Embase, and Web of Science). This article presents a comprehensive approach to the diagnosis, appropriate investigations, their interpretations, and use of specific therapies according to the stage of disease.

Keywords: COVID-19; Novel coronavirus; SARS-CoV-2.

PubMed Disclaimer

References

    1. Griffin Daniel O., Brennan- Rieder Denise, Ngo Binh, et al. The importance of understanding the stages of COVID-19 in treatment and trials. AIDS Rev. February 2021;23:40–47. - PubMed
    1. Clinical Management Protocol for Covid-19 in Adults; Ministry of Health and Family Welfare; Version 6; Dated 24.05.21.
    1. Clinical Guidance for Management of Adult Covid-19 Patients. Ministry of Health & Family Welfare, Government of India; 2022. Dated 14.01.
    1. Centers for Disease Control and Prevention. People who are at higher risk for severe illness https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-... (Accessed on April 01, 2020).
    1. Stokes E.K., Zambrano L.D., Anderson K.N., et al. vol. 69. MMWR Morb Mortal Wkly Rep; 2020. Coronavirus Disease 2019 Case Surveillance - United States; p. 759. January 22-May 30, 2020. - PMC - PubMed

LinkOut - more resources