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Review
. 2022 Sep 27:10.1111/ceo.14175.
doi: 10.1111/ceo.14175. Online ahead of print.

The standardisation of uveitis nomenclature (SUN) project

Douglas A Jabs  1   2 , Peter McCluskey  3 , Alan G Palestine  4 , Jennifer E Thorne  1   2 ; Standardization of Uveitis Nomenclature (SUN) Working Group
Collaborators, Affiliations
Review

The standardisation of uveitis nomenclature (SUN) project

Douglas A Jabs et al. Clin Exp Ophthalmol. .

Abstract

The uveitides are a collection of over 30 diseases characterised by intraocular inflammation. Previous work demonstrated that the agreement among uveitis experts on diagnosis was modest at best with some pairs of experts having chance alone agreement on selected diseases. The Standardisation of Uveitis Nomenclature (SUN) is a17-year collaboration among experts in uveitis, ocular image grading, informatics, and machine learning to improve clinical and translational uveitis research. The SUN "Developing Classification Criteria for the Uveitides" project used a rigorous, multi-phase approach to develop classification criteria for 25 of the most common uveitic diseases. The project's phases were: (1) informatics; (2) case collection; (3) case selection; (4) machine learning; and (5) consensus review and publication. The results were classification criteria with a high degree of accuracy (93.3%-99.3% depending on anatomic class of the uveitis), the goal of which is to form the basis for future uveitis research.

Keywords: epidemiology; inflammation; uveitis.

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Conflict of interest statement

Conflict of interest: None

References

    1. Jabs DA, Busingye J. Approach to the diagnosis fo the uveitides. Am J Ophthalmol 2013;156(2):228–36. - PMC - PubMed
    1. Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol 2005;140(3):509–16. - PMC - PubMed
    1. Rosenbaum JT, Wernick R. The utility of routine screening of patients with uveitis for systemic lupus erythematosus or tuberculosis. A Bayesian analysis. Arch Ophthalmol 1990;108(9):1291–3. - PubMed
    1. Albini TA, Karakousis PC, Rao NA. Interferon-gamma release assays in the diagnosis of the tuberculosis uveitis. Am J Ophthalmol 2008;146(4):486–8. - PubMed
    1. Zamecki KJ, Jabs DA. HLA typing in uveitis: use and misuse. Am J Ophthalmol 2010;149(2):189–93. - PubMed