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Review
. 2023 Apr;27(2):197-206.
doi: 10.1111/1744-9987.13934. Epub 2022 Oct 12.

Therapeutic plasma exchange in anti-N-methyl-D-aspartate receptor encephalitis

Yuan Zhang  1 , Yong-Kang Cheng  1 , Chun-Feng Yang  1 , Lin-Mei Jin  1 , Yu-Mei Li  1
Affiliations
Review

Therapeutic plasma exchange in anti-N-methyl-D-aspartate receptor encephalitis

Yuan Zhang et al. Ther Apher Dial. 2023 Apr.

Abstract

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most commonly identified cause of autoimmune encephalitis. Therapeutic plasma exchange has been increasingly employed to treat this disease. This expansion is a consequence of improved techniques and apheresis instruments, as well as the recognition of its applicability in neurological diseases. However, several aspects of treatment remain incompletely clarified, and treatment strategies are still heterogeneous, especially with regard to therapeutic plasma exchange in anti-NMDAR encephalitis. This review provides an overview of the use of therapeutic plasma exchange including the principle and mechanisms, the evidence, initial time, efficiency and complications in anti-NMDAR encephalitis.

Keywords: anti-NMDAR encephalitis; therapeutic plasma exchange.

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References

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