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Review
. 2022 Oct 1;35(10):33-37.
doi: 10.1097/01.JAA.0000873780.18121.bd.

Multisystem inflammatory syndrome in children

Kelly R Porta  1 , Christine Zammit
Affiliations
Review

Multisystem inflammatory syndrome in children

Kelly R Porta et al. JAAPA. .

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a potentially life-threatening syndrome that emerged soon after the start of the COVID-19 pandemic. This case report focuses on the general overview, case definition, epidemiology, pathogenesis, clinical findings, and management of MIS-C.

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References

    1. Jiang L, Tang K, Levin M, et al. COVID-19 and multisystem inflammatory syndrome in children and adolescents. Lancet Infect Dis . 2020;20(11):e276–e288.
    1. Centers for Disease Control and Prevention. COVID data tracker. United States COVID-19 cases, deaths, and laboratory testing (NAATs) by state, territory, and jurisdiction. https://covid.cdc.gov/covid-data-tracker/#cases_casesper100klast7days . Accessed July 22, 2022.
    1. Centers for Disease Control and Prevention. Coronavirus disease 2019 in children—United States, February 12-April 2, 2020. MMWR Morb Mortal Wkly Rep . 2020;69(14):422–426.
    1. Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr . 2020;109(6):1088–1095.
    1. Riphagen S, Gomez X, Gonzalez-Martinez C, et al. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet . 2020;395(10237):1607–1608.

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