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Comment

. 2022 Sep 27;15(753):eade9960.

doi: 10.1126/scisignal.ade9960. Epub 2022 Sep 27.

Stress with ketamine tackles depression

Leslie K Ferrarelli¹

Affiliations

PMID: 36166513
DOI: 10.1126/scisignal.ade9960

Comment

Stress with ketamine tackles depression

Leslie K Ferrarelli. Sci Signal. 2022.

. 2022 Sep 27;15(753):eade9960.

doi: 10.1126/scisignal.ade9960. Epub 2022 Sep 27.

Author

Leslie K Ferrarelli¹

Affiliation

¹ Science Signaling, AAAS, Washington, DC 20005, USA. Email: lferrare@aaas.org.

PMID: 36166513
DOI: 10.1126/scisignal.ade9960

Abstract

A stress hormone enables the antidepressant action of ketamine.

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Comment on

Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor.
Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, Clark SM, Tonelli LH, Moaddel R, Zarate CA Jr, Duman RS, Thompson SM, Gould TD. Georgiou P, et al. Nat Neurosci. 2022 Sep;25(9):1191-1200. doi: 10.1038/s41593-022-01146-x. Epub 2022 Aug 30. Nat Neurosci. 2022. PMID: 36042309 Free PMC article.

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