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Case Reports
. 2022 Aug 24;14(8):e28364.
doi: 10.7759/cureus.28364. eCollection 2022 Aug.

Non-Hodgkin's Vaginal Lymphoma: A Rare Presentation

Asma Usman  1 , Anum Sultan  1 , Sara Rehman  1 , Anis Rehman  1
Affiliations
Case Reports

Non-Hodgkin's Vaginal Lymphoma: A Rare Presentation

Asma Usman et al. Cureus. .

Abstract

Vaginal non-Hodgkin's lymphoma (NHL) is a rare entity. We report a case of a 38-year-old lady who presented with complaints of lower abdominal pain for three to four months and vaginal bleeding for one month. Her examination under general anesthesia revealed a hard vaginal mass which was biopsied and immunohistochemistry was performed. Diagnosis of diffuse B‑cell NHL (DLBCL) was made. Imaging plays an important role to reach the diagnosis. Chemotherapy is the treatment of choice.

Keywords: chemotherapy; immunohistochemistry and biopsy; mri; pet ct; vaginal lymphoma.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. MRI T2W sagittal (a), axial STIR (b), DWI (c), and ADC (d) images demonstrating large vaginal mass showing low signals on T2W (blue arrow) and high signals with diffusion restriction (green arrows).
T2W: T2 weighted, STIR: Short tau inversion recovery, DWI: Diffusion-weighted imaging, ADC: Apparent diffusion coefficient
Figure 2
Figure 2. Pelvic CT (a), PET (b) and PET CT fusion (c) axial images showing hypermetabolic cervical/upper vaginal mass (white arrow) with parametrial extension and left pelvic sidewall involvement.
Figure 3
Figure 3. Interim pelvic CT (a), PET (b) and PET CT fusion (c) axial images showing good partial treatment response with interval regression in size and metabolic activity of the cervix/vaginal mass (red arrow).
Figure 4
Figure 4. End of treatment pelvic CT (a), PET (b) and PET CT fusion (c) axial images showing complete metabolic response.
See this image and copyright information in PMC

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