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Comment
. 2022 Nov;21(11):795.
doi: 10.1038/d41573-022-00159-2.

Developing antibody-based PROTACs

Sarah Crunkhorn
Comment

Developing antibody-based PROTACs

Sarah Crunkhorn. Nat Rev Drug Discov. 2022 Nov.
No abstract available

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Comment on

  • Antibody targeting of E3 ubiquitin ligases for receptor degradation.
    Marei H, Tsai WK, Kee YS, Ruiz K, He J, Cox C, Sun T, Penikalapati S, Dwivedi P, Choi M, Kan D, Saenz-Lopez P, Dorighi K, Zhang P, Kschonsak YT, Kljavin N, Amin D, Kim I, Mancini AG, Nguyen T, Wang C, Janezic E, Doan A, Mai E, Xi H, Gu C, Heinlein M, Biehs B, Wu J, Lehoux I, Harris S, Comps-Agrar L, Seshasayee D, de Sauvage FJ, Grimmer M, Li J, Agard NJ, de Sousa E Melo F. Marei H, et al. Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6. Epub 2022 Sep 21. Nature. 2022. PMID: 36131013 Free PMC article.

References

    1. Marei, H. et al. Antibody targeting of E3 ubiquitin ligases for receptor degradation. Nature https://doi.org/10.1038/s41586-022-05235-6 (2022)

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