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. 1978 Nov;136(2):825-7.
doi: 10.1128/jb.136.2.825-827.1978.

Orotic acid excretion in some wild-type strains of Escherichia coli K-12

J E Womack, G A O'Donovan

Orotic acid excretion in some wild-type strains of Escherichia coli K-12

J E Womack et al. J Bacteriol. 1978 Nov.

Abstract

During rapid growth, the excretion of pyrimidines, predominantly uracil, is a common phenomenon in procaryotes and eucaryotes. In Escherichia coli, some K-12 strains excrete orotic acid and not uracil. This is caused by a mutation in the pyrF gene.

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