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Review
. 2022 Sep 13:12:815786.
doi: 10.3389/fcimb.2022.815786. eCollection 2022.

Semen dysbiosis-just a male problem?

Emilia Morawiec  1   2   3 , Michał Czerwiński  2   4 , Anna Bednarska- Czerwińska  2   5 , Andrzej Wiczkowski  1
Affiliations
Review

Semen dysbiosis-just a male problem?

Emilia Morawiec et al. Front Cell Infect Microbiol. .

Abstract

Seminal microflora is crucial to male fertility. Dysbiosis-disturbance of quantitative ratios of individual bacteria or appearance of pathogenic species-rarely results in symptomatic disease. Inflammation results in decreased sperm production, lower motility, or morphological changes and, in the long term, can cause ejaculatory duct obstruction, leading to infertility. Moreover, it may cause infection of the partner's female genital tract. Dysbiosis in both partners results in fertility problems, disorders in embryo implantation, or miscarriages. In addition, chronic inflammation of the male genitourinary system may accelerate the appearance of antisperm antibodies. A comprehensive examination of seminal microflora can clarify the causes of infertility or prevent pathological conditions that affect seminal parameters. Seminal microflora as a direct impact on fertility problems as well as a decrease in the effectiveness of assisted reproduction methods, insemination, or in vitro procedures.

Keywords: dysbiosis; infertility; microbiome; semen; sequencing.

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Conflict of interest statement

EM was employed by the company Gyncentrum. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Influence of dysbiosis on semen parameters.
See this image and copyright information in PMC

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