Emerging insights to lung cancer drug resistance
- PMID: 36176761
- PMCID: PMC9511798
- DOI: 10.20517/cdr.2022.61
Emerging insights to lung cancer drug resistance
Abstract
Lung cancer remains the malignant tumor with the highest morbidity and mortality in China, with non-small cell lung cancer (NSCLC) accounting for 80%-85% of cases. Nowadays, the treatment pattern of NSCLC has evolved toward precision management with the development of molecular targeted therapy and immunotherapy. However, the median overall survival for patients with metastatic NSCLC, unfortunately, remains less than three years. Drug resistance is the bottleneck to preventing drugs from playing a further role, and the mechanistic study of drug resistance is the prerequisite for new regimen development. This Special Issue pays special attention to drug resistance in the treatment of NSCLC. We received and published several excellent articles regarding this topic. We hope that, through this Special Issue, we can have a deep understanding of the existing problems, the underlying mechanism, and the future solutions and that the publication of this Special Issue can bring some inspiration to readers.
Keywords: Non-small cell lung cancer; drug resistance; immunotherapy; targeted therapy.
© The Author(s) 2022.
Conflict of interest statement
Author Chunxia Su was employed by Shanghai pulmonary hospital, China. The author declares that this study did not receive any funding from any sponsor or commercial entity. No person other than the author was involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication. The author declares no other competing interests.
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