Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
- PMID: 36179693
- PMCID: PMC9561634
- DOI: 10.1016/j.stemcr.2022.09.002
Panning for gold: Purifying mesencephalic dopaminergic progenitors differentiated from human pluripotent stem cells
Abstract
In a recently published study, Xu et al. used two surface markers, CLSTN2 and PTPRO, to generate highly purified donor dopaminergic neurons and achieved stable and predictable therapeutic outcomes by transplantation into the brain of PD animal models (Xu et al., 2022).
Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Conflict of interest The authors declare no competing interests.
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Human midbrain dopaminergic neuronal differentiation markers predict cell therapy outcomes in a Parkinson's disease model.J Clin Invest. 2022 Jul 15;132(14):e156768. doi: 10.1172/JCI156768. J Clin Invest. 2022. PMID: 35700056 Free PMC article.
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