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Meta-Analysis
. 2023 Apr;55(4):897-912.
doi: 10.1007/s11255-022-03374-3. Epub 2022 Oct 1.

The effect of psychosocial interventions on depression, anxiety, and quality of life in hemodialysis patients: a systematic review and a meta-analysis

Serena Barello  1   2 , Gloria Anderson  3 , Marta Acampora  4 , Caterina Bosio  4 , Elena Guida  4 , Vincenzo Irace  5 , Carlo Maria Guastoni  6 , Barbara Bertani  7   8 , Guendalina Graffigna  4   7   9
Affiliations
Meta-Analysis

The effect of psychosocial interventions on depression, anxiety, and quality of life in hemodialysis patients: a systematic review and a meta-analysis

Serena Barello et al. Int Urol Nephrol. 2023 Apr.

Abstract

Purpose: Hemodialysis has become a standard therapy for adults with end-stage renal diseases. Adults undergoing hemodialysis have to cope with unique psychological issues that make their care journey particularly fatiguing. In this systematic review and meta-analysis, we aimed to summarize and evaluate the effects of psychosocial interventions on the reduction of anxiety and depression in adults with HDs.

Methods: We included randomized controlled trials and quasi-experimental studies that measure change in depression, anxiety, and quality of life.

Results: We identify three categories of psychosocial interventions delivered to adults undergoing hemodialysis. Based on our analysis, there was a medium effect of psychosocial intervention on depression (SMD - 0.85, 95%CI - 1.17; - 0.52, I2 = 80%, p < 0.01) and anxiety (SMD - 0.99, 95%CI - 1.65; - 0.33, I2 = 88%, p < 0.01) in adults undergoing hemodialysis.

Conclusions: Psychosocial interventions, such as psychological support or relaxation-based therapy, seems all to reduce depression and anxiety in adults undergoing HD. Preliminary evidence suggests that there may be a benefit of psychosocial interventions on the quality of life for adults undergoing HD.

Keywords: Anxiety; Depression; End-stage renal diseases; Hemodialysis; Psychosocial intervention; Quality of life.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

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Search strategy
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Depression forest plot
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Anxiety forest plot
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Quality-of-life forest plot
See this image and copyright information in PMC

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