The Potential Synergy of Using Interventional and Observational Data to Study Clinically Meaningful, Long-term Outcomes in Rare Liver and Luminal Diseases

Affiliations

¹ Department of Medicine, Division of Gastroenterology & Hepatology and, Department of Biostatistics, Epidemiology & Informatics, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: therese.bittermann@pennmedicine.upenn.edu.

Editorial

Therese Bittermann. Gastroenterology. 2022 Dec.

. 2022 Dec;163(6):1491-1492.

doi: 10.1053/j.gastro.2022.09.031. Epub 2022 Sep 28.

¹ Department of Medicine, Division of Gastroenterology & Hepatology and, Department of Biostatistics, Epidemiology & Informatics, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: therese.bittermann@pennmedicine.upenn.edu.

No abstract available

Comment on

Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
Murillo Perez CF, Fisher H, Hiu S, Kareithi D, Adekunle F, Mayne T, Malecha E, Ness E, van der Meer AJ, Lammers WJ, Trivedi PJ, Battezzati PM, Nevens F, Kowdley KV, Bruns T, Cazzagon N, Floreani A, Mason AL, Parés A, Londoño MC, Invernizzi P, Carbone M, Lleo A, Mayo MJ, Dalekos GN, Gatselis NK, Thorburn D, Verhelst X, Gulamhusein A, Janssen HLA, Smith R, Flack S, Mulcahy V, Trauner M, Bowlus CL, Lindor KD, Corpechot C, Jones D, Mells G, Hirschfield GM, Wason J, Hansen BE; GLOBAL PBC Study Group and the members of the UK-PBC Consortium. Murillo Perez CF, et al. Gastroenterology. 2022 Dec;163(6):1630-1642.e3. doi: 10.1053/j.gastro.2022.08.054. Epub 2022 Sep 20. Gastroenterology. 2022. PMID: 36150526 Clinical Trial.