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. 2022 Oct;42(5):1094-1098.
doi: 10.1007/s11596-022-2635-z. Epub 2022 Oct 3.

Analysis of Common Respiratory Infected Pathogens in 3100 Children after the Coronavirus Disease 2019 Pandemic

Jun-E Ma #  1 , Qing-Feng Ma #  2 , Wei Wang #  3 , Yan Zeng #  4 , Xiang-Hua Cui  1 , Guo-Lei Wang  1 , Si-Yu Liu  5 , Zhen Wang  1 , Xuan Xiao  6 , Zu-Neng Xia  7 , Heng-Cheng Zhu  8 , Cheng-Liang Zhu  9
Affiliations

Analysis of Common Respiratory Infected Pathogens in 3100 Children after the Coronavirus Disease 2019 Pandemic

Jun-E Ma et al. Curr Med Sci. 2022 Oct.

Abstract

Objective: To investigate the epidemiological features in children after the coronavirus disease 2019 (COVID-19) pandemic.

Methods: This study collected throat swabs and serum samples from hospitalized pediatric patients of Renmin Hospital of Wuhan University, Wuhan, Hubei province, China before and after the COVID-19 pandemic. Respiratory infected pathogens [adenovirus (ADV), influenza virus A/B (Flu A/B), parainfluenza virus 1/2/3 (PIV1/2/3), respiratory syncytial virus (RSV), Mycoplasma pneumoniae (MP), and Chlamydia pneumoniae (CP)] were detected. The pathogens, age, and gender were used to analyze the epidemiological features in children after the COVID-19 pandemic.

Results: The pathogen detection rate was significantly higher in females than in males (P<0.05), and the infection of PIV1 and MP was mainly manifested. After the COVID-19 pandemic, PIV1, PIV3, RSV, and MP had statistically different detection rates among the age groups (P<0.05), and was mainly detected in patients aged 0-6 years, 0-3 years, 0-3 years, and 1-6 years, respectively. When comparing before the COVID-19 pandemic, the total detection rate of common respiratory pathogens was lower (P<0.05). Except for the increase in the detection rate of PIV1 and CP, the infection rate of other pathogens had almost decreased.

Conclusion: The prevention and control measures for the COVID-19 pandemic effectively changed the epidemiological features of common respiratory tract infectious diseases in pediatric children.

Keywords: before and after the COVID-19 pandemic; common respiratory infectious pathogens; pediatric children.

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Conflict of interest statement

The authors declared no conflict of interest.

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