Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug 28;14(8):e28506.
doi: 10.7759/cureus.28506. eCollection 2022 Aug.

The Relationship Between In-Hospital Mortality and Frontal QRS-T Angle in Patients With COVID-19

Ercan Tastan  1 , Ümit İnci  2
Affiliations

The Relationship Between In-Hospital Mortality and Frontal QRS-T Angle in Patients With COVID-19

Ercan Tastan et al. Cureus. .

Abstract

Background Recent studies have demonstrated that the frontal QRS-T angle, defined as the angle between the mean QRS and T vectors, is a strong independent predictor of mortality in patients with cardiovascular disease and in the normal population. In this study, we aimed to investigate the relationship between frontal QRS-T angle and in-hospital mortality in COVID-19 patients. Methods A total of consecutive 532 patients with positive polymerase chain reaction (PCR) tests were enrolled. The patients were divided into two groups as in-hospital mortality and survival groups. Frontal QRS-T angle was automatically calculated from the admission electrocardiography (ECG). Results The median age in the study population was 62 (49-72) years and 273 (51.4%) of the patients were male. The median frontal QRS-T angle was 40 degrees (20-67 IQR) in the in-hospital mortality group, while it was 27 (11-48 IQR) in the survival group (p=0.001). In multivariable logistic regression analysis, frontal QRS-T angle was found to be an independent predictor of mortality (Odds ratio (OR):1.01, 95% Confidence interval (CI):1.00-1.02, p=0.036). Conclusion Frontal QRS-T angle, which was observed wider in the in-hospital mortality group, was found to be associated with in-hospital mortality in patients hospitalized for COVID-19.

Keywords: covid-19; echo cardiogram; ekg abnormalities; frontal qrs-t angle; in-hospital mortality.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Similar articles

See all similar articles

Cited by

References

    1. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Guzik TJ, Mohiddin SA, Dimarco A, et al. Cardiovasc Res. 2020;116:1666–1687. - PMC - PubMed
    1. Electrocardiographic predictors of morbidity and mortality in patients with acute myocarditis: the importance of QRS-T angle. Chen S, Hoss S, Zeniou V, et al. J Card Fail. 2018;24:3–8. - PubMed
    1. Comparison of the prognostic significance of the electrocardiographic QRS/T angles in predicting incident coronary heart disease and total mortality (from the atherosclerosis risk in communities study) Zhang ZM, Prineas RJ, Case D, Soliman EZ, Rautaharju PM. Am J Cardiol. 2007;100:844–849. - PMC - PubMed
    1. Relations between QRS|T angle, cardiac risk factors, and mortality in the third National Health and Nutrition Examination Survey (NHANES III) Whang W, Shimbo D, Levitan EB, Newman JD, Rautaharju PM, Davidson KW, Muntner P. Am J Cardiol. 2012;109:981–987. - PMC - PubMed
    1. Predicting ventricular arrhythmias in patients with ischemic heart disease: clinical application of the ECG-derived QRS-T angle. Borleffs CJ, Scherptong RW, Man SC, et al. Circ Arrhythm Electrophysiol. 2009;2:548–554. - PubMed

LinkOut - more resources