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. 2022 Aug 30;14(8):e28572.
doi: 10.7759/cureus.28572. eCollection 2022 Aug.

Correlation Between Different Parameters of Acute Myocardial Infarction and Obesity

Saad A Alqahtani  1 , Attafah M Omeish  2 , Enas M Ghulam  3   4 , Wael M Alsalim  5 , Hatan J Momenkhan  6 , Olga Vriz  7 , Abdulhalim J Kinsara  8
Affiliations

Correlation Between Different Parameters of Acute Myocardial Infarction and Obesity

Saad A Alqahtani et al. Cureus. .

Abstract

Objective: To study if obesity had a detrimental effect on troponin after acute coronary syndrome. We investigated the effects of the body mass index (BMI) in post-myocardial infarction (MI) patients, and see the difference in troponin levels and other parameters between normal and overweight patients.

Methodology: A retrospective cohort study was conducted. Data were extracted from the electronic medical files of patients hospitalized due to acute ST-elevation MI to examine the association between BMI and MI. Sixty-one patients were categorized into normal BMI category, overweight, and obese/morbid obesity groups using the baseline measurements, to assess the independent factors associated with a patient with a high BMI who had a MI.

Results: In total, 61 post-myocardial infarction patients with a mean age of 56.9 ± 11.2 years were included in the study. The average BMI was 28.5 ± 6.5 kg/m2. Just more than a third (37.4%, n=23) were in the normal BMI category, 19 (31.2%) overweight, and 19 (31.2%) obese/morbid obesity. The mean left ventricle mass was 93.74 ± 32.69 gram and the mean left ventricular ejection fraction was 44.02% ± 10.02. A significant difference in the mean level of troponin and mean heart rate between the body mass index groups (normal vs. overweight groups) was noted. A fair correlation was noted between BMI and left ventricle mass. No statistically significant relation could be linked to high BMI with total cholesterol, low-density lipoprotein (LDL), or aspartate transferase/alanine transaminase (AST/ALT) levels.

Conclusions: In this pilot study, the group with a high BMI had a statistically significant lower troponin level and higher mean heart rate. Such data need to be considered when assessing a patient's risk. In addition, obese persons with a MI had a higher left ventricle mass.

Keywords: body mass index; left ventricle mass; myocardial infarction; obese; troponin.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Scatter plots of the relation between BMI and Troponin/LDLC/ALT/LV mass
BMI: Body mass index; LDLC: Low-density-lipoprotein cholesterol; ALT: Alanine transaminase; LV mass: Left-ventricular mass
See this image and copyright information in PMC

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