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. 2022 Sep:10.2217/fvl-2022-0045.
doi: 10.2217/fvl-2022-0045. Epub 2022 Sep 26.

Rapid antigen test for SARS-CoV-2: results of validation and use in real life

Irena Grmek Kosnik  1 , Urska Dermota  1 , Andrej Golle  1 , Tjasa Zohar Cretnik  1
Affiliations

Rapid antigen test for SARS-CoV-2: results of validation and use in real life

Irena Grmek Kosnik et al. Future Virol. 2022 Sep.

Abstract

Aim: To verify a SARS-CoV-2 rapid antigen test (RAT) compared with PCR. Materials & methods: Validation of RAT included 2295 subjects. Next matching of RAT with the PCR was checked in 13,852 subjects referred to PCR after being positive in RAT. Results: Sensitivity and specificity of RAT were 77.38 and 99.10%, respectively. A 74.60% of RAT positive results were confirmed with PCR. Conclusion: The test met WHO susceptibility criteria in a group of symptomatic subjects. In terms of specificity, it met requirements in all subjects. The concordance of RAT with PCR in real life was in line with our verification data.

Keywords: PCR; RAT; SARS-CoV-2; rapid antigen test; validation.

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