Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Nov-Dec;22(6):291-294.
doi: 10.1016/j.ipej.2022.09.003. Epub 2022 Oct 1.

A dynamic Brugada sign due to left anterior descending coronary artery occlusion

Affiliations
Case Reports

A dynamic Brugada sign due to left anterior descending coronary artery occlusion

Vickram Vignesh Rangaswamy et al. Indian Pacing Electrophysiol J. 2022 Nov-Dec.

Erratum in

Abstract

Brugada phenocopies (BrP) include several conditions with a common electrocardiographic (ECG) pattern that are indistinguishable from classical Brugada syndrome (BrS). In this report, we describe two cases of acute myocardial infarction (AMI) presenting as BrP. The majority of cases of BrP in AMI have been reported due to right coronary artery (RCA) occlusion. Rarely, the left anterior descending artery (LAD) is incriminated as the cause. In both our cases of BrP, LAD was the culprit vessel.

Keywords: Acute coronary syndrome; Acute myocardial infarction; Brugada phenocopy; Brugada sign; Brugada syndrome.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
A: ECG taken at presentation showing horizontal ST segment depression with T wave inversion in anterior leads Fig. 1B: ECG taken during an episode of chest pain showing the emergence of Brugada sign in V1–V3 along with ST segment elevation (STE) in aVR and ST segment depression along with reversal of T wave polarity in V3–V5 and aVL. Fig. 1C: ECG taken post PCI to LAD vessel showed the resolution of Brugada sign.
Fig. 2
Fig. 2
A: ECG taken during chest pain shows Brugada sign in V1–V2 and deep T wave inversion in anterolateral leads (V4-6 and I and aVL) Fig. 2B: ECG taken post PCI to LAD vessel showed resolution of ECG changes.
figs1
figs1

References

    1. de Oliveira Neto N., de Oliveira W., Mastrocola F., Sacilotto L. Brugada phenocopy: mechanisms, diagnosis, and implications. J Electrocardiol. 2019;55:45–50. doi: 10.1016/j.jelectrocard.2019.04.017. - DOI - PubMed
    1. Anselm D. Brugada phenocopy: a new electrocardiogram phenomenon. World J Cardiol. 2014;6(3):81. doi: 10.4330/wjc.v6.i3.81. - DOI - PMC - PubMed
    1. Ohkubo K., Watanabe I., Okumura Y., et al. Brugada syndrome in the presence of coronary artery disease. J Arrhythm. 2013;29(4):211–216. doi: 10.1016/j.joa.2012.09.008. - DOI
    1. Di Diego J., Fish J., Antzelevitch C. Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences. J Electrocardiol. 2005;38(4):14–17. doi: 10.1016/j.jelectrocard.2005.06.003. - DOI - PMC - PubMed
    1. Brugada J., Campuzano O., Arbelo E., Sarquella-Brugada G., Brugada R. Present status of Brugada syndrome. J Am Coll Cardiol. 2018;72(9):1046–1059. doi: 10.1016/j.jacc.2018.06.037. - DOI - PubMed

Publication types