Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Oct 28;32(10):1226-1233.
doi: 10.4014/jmb.2205.05041. Epub 2022 Aug 30.

The Functional Roles of Lactobacillus acidophilus in Different Physiological and Pathological Processes

Huijuan Gao  1 , Xin Li  1 , Xiatian Chen  1 , Deng Hai  2 , Chuang Wei  1 , Lei Zhang  1 , Peifeng Li  1
Affiliations
Review

The Functional Roles of Lactobacillus acidophilus in Different Physiological and Pathological Processes

Huijuan Gao et al. J Microbiol Biotechnol. .

Abstract

Probiotics are live microorganisms that can be consumed by humans in amounts sufficient to offer health-promoting effects. Owing to their various biological functions, probiotics are widely used in biological engineering, industry and agriculture, food safety, and the life and health fields. Lactobacillus acidophilus (L. acidophilus), an important human intestinal probiotic, was originally isolated from the human gastrointestinal tract and its functions have been widely studied ever since it was named in 1900. L. acidophilus has been found to play important roles in many aspects of human health. Due to its good resistance against acid and bile salts, it has broad application prospects in functional, edible probiotic preparations. In this review, we explore the basic characteristics and biological functions of L. acidophilus based on the research progress made thus far worldwide. Various problems to be solved regarding the applications of probiotic products and their future development are also discussed.

Keywords: Lactobacillus acidophilus; Probiotics; cholesterol; immunity; intestinal flora.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest

The authors have no financial conflicts of interest to declare.

Figures

Fig. 1
Fig. 1. Probiotic properties and biological functions of Lactobacillus acidophilus.
L. acidophilus is a species of beneficial microbial flora and has been proven to play an important role in many pathological and physiological processes. It has been shown to improve CVD and lactose intolerance, prevent and treat cancer, regulate immunity, and improve gastrointestinal diseases.
See this image and copyright information in PMC

References

    1. Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, et al. Expert consensus document. The international scientific association for probiotics and prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat. Rev. Gastroenterol. Hepatol. 2014;11:506–514. doi: 10.1038/nrgastro.2014.66. - DOI - PubMed
    1. Butel MJ. Probiotics, gut microbiota and health. Med. Mal. Infect. 2014;44:1–8. doi: 10.1016/j.medmal.2013.10.002. - DOI - PubMed
    1. Saini R, Saini S, Sugandha Probiotics: the health boosters. J. Cutan. Aesthet. Surg. 2009;2:112. doi: 10.4103/0974-2077.58530. - DOI - PMC - PubMed
    1. Shah NP. Functional cultures and health benefits. Int. Dairy J. 2007;17:1262–1277. doi: 10.1016/j.idairyj.2007.01.014. - DOI
    1. Mital BK, Garg SK. Anticarcinogenic, hypocholesterolemic, and antagonistic activities of Lactobacillus acidophilus. Crit. Rev. Microbiol. 1995;21:175–214. doi: 10.3109/10408419509113540. - DOI - PubMed

Substances