Transient Receptor Potential Ankyrin 1 Channels in Inflammation and Cancer: Accelerators or Brakes?
- PMID: 36196090
- PMCID: PMC9523459
- DOI: 10.1093/function/zqac049
Transient Receptor Potential Ankyrin 1 Channels in Inflammation and Cancer: Accelerators or Brakes?
Keywords: Ca2+ signaling; TRPA1; alcoholic pancreatitis; pancreatic fibrosis; pancreatic stellate cells.
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Activation of pancreatic stellate cells attenuates intracellular Ca2+ signals due to downregulation of TRPA1 and protects against cell death induced by alcohol metabolites.Cell Death Dis. 2022 Aug 29;13(8):744. doi: 10.1038/s41419-022-05186-w. Cell Death Dis. 2022. PMID: 36038551 Free PMC article.
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- Petersen OH, Gerasimenko JV, Gerasimenko OVet al. The roles of calcium and ATP in the physiology and pathology of the exocrine pancreas. Physiol Rev. 2021;101(4):1691–1744. - PubMed
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