Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Dec 1;41(12):1584-1599.
doi: 10.1097/ICO.0000000000003122. Epub 2022 Sep 28.

Glaucoma in Patients With Endothelial Keratoplasty

Chhavi Saini  1 , Emma C Davies, James Chodosh, Lucy Q Shen
Affiliations
Review

Glaucoma in Patients With Endothelial Keratoplasty

Chhavi Saini et al. Cornea. .

Abstract

Endothelial keratoplasty (EK), including Descemet stripping endothelial keratoplasty and Descemet membrane endothelial keratoplasty, is now the most performed corneal transplant procedure in the United States. Intraocular pressure (IOP) elevation and glaucoma are common complications and can cause irreversible vision loss and corneal graft failure. This review will cover the incidence, risk factors, and management of glaucoma and IOP elevation after EK. Higher preoperative IOP, preoperative glaucoma, and certain indications for EK, such as bullous keratopathy, are associated with increased risk of glaucoma and glaucoma progression in patients undergoing EK. In addition, we summarize the studies assessing graft outcomes in EK patients with glaucoma or glaucoma surgery. Finally, we provide future directions to improve clinical care in EK patients with glaucoma.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

References

    1. Tillett CW. Posterior lamellar keratoplasty. Am J Ophthalmol. 1956;41:530–533.
    1. Melles Gerrit RJ, Lander F, Beekhuis WH, et al. Posterior lamellar keratoplasty for a case of pseudophakic bullous keratopathy. Am J Ophthalmol. 1999;127:340–341.
    1. Bank E. 2019 Eye Banking Statistical Report. 2019 Analysis of Surgical Use and Indications for Corneal Transplant. 2020:775–4999. Available at: www.restoresight.org . Accessed May 23, 2022.
    1. Chan SWS, Yucel Y, Gupta N. New trends in corneal transplants at the University of Toronto. Can J Ophthalmol. 2018;53:580–587.
    1. Ingraham HJ, Donnenfeld ED, Perry HD. Massive suprachoroidal hemorrhage in penetrating keratoplasty. Am J Ophthalmol. 1989;108:670–675.