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. 2022 Oct 3;141(3):e2022226.
doi: 10.1590/1516-3180.2022.0226.R1.21072022. eCollection 2022.

Association between multimorbidity, intensive care unit admission, and death in patients with COVID-19 in Brazil: a cross-section study, 2020

Jefferson Paixão Cardoso  1 , Maria Inês Pardo Calazans  2 , Aretha Lorena Fonseca Cantanhede Carneiro  3 , Cayara Mattos Costa  4 , Edna Luisa Oliveira Monteiro  3 , Liliana Yanet Gómez Aristizábal  5 , Juliana da Silva Oliveira  6 , Alcione Miranda Dos Santos  7
Affiliations

Association between multimorbidity, intensive care unit admission, and death in patients with COVID-19 in Brazil: a cross-section study, 2020

Jefferson Paixão Cardoso et al. Sao Paulo Med J. .

Abstract

Background: Multimorbidity can influence intensive care unit (ICU) admissions and deaths due to coronavirus disease (COVID-19).

Objective: To analyze the association between multimorbidity, ICU admissions, and deaths due to COVID-19 in Brazil.

Design and setting: This cross-sectional study was conducted using data from patients with severe acute respiratory syndrome (SARS) due to COVID-19 recorded in the Influenza Epidemiological Surveillance Information System (SIVEP-Gripe) in 2020.

Methods: Descriptive and stratified analyses of multimorbidity were performed based on sociodemographic, ventilatory support, and diagnostic variables. Poisson regression was used to estimate the prevalence ratios.

Results: We identified 671,593 cases of SARS caused by COVID-19, of which 62.4% had at least one morbidity. Multimorbidity was associated with male sex, age 60-70 and ≥ 80 years, brown and black skin color, elementary education and high school, ventilatory support, and altered radiologic exams. Moreover, all regions of the country and altered computed tomography due to COVID-19 or other diseases were associated with death; only the northeast region and higher education were associated with ICU admission.

Conclusion: Our results showed an association between multimorbidity, ICU admission, and death in COVID-19 patients in Brazil.

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Conflict of interest statement

Conflicts of interest: The authors declare no conflicts of interest related to this research

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