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Comment
. 2022 Oct 4;34(10):1424-1426.
doi: 10.1016/j.cmet.2022.09.012.

Paraventricular glia drive circuit function to control metabolism

Luis Varela  1 , Tamas L Horvath  2
Affiliations
Comment

Paraventricular glia drive circuit function to control metabolism

Luis Varela et al. Cell Metab. .

Abstract

The role of glia as active participants in brain functions has become increasingly evident. In this issue of Cell Metabolism, Herrera Moro Chao et al. reveal that astrocytes in the hypothalamic paraventricular nucleus (PVN) bidirectionally control neuronal behavior in response to metabolic cues and that this control is disrupted in obesity.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Hypothalamic astrocytes control systemic glucose metabolism and energy balance.
    Herrera Moro Chao D, Kirchner MK, Pham C, Foppen E, Denis RGP, Castel J, Morel C, Montalban E, Hassouna R, Bui LC, Renault J, Mouffle C, García-Cáceres C, Tschöp MH, Li D, Martin C, Stern JE, Luquet SH. Herrera Moro Chao D, et al. Cell Metab. 2022 Oct 4;34(10):1532-1547.e6. doi: 10.1016/j.cmet.2022.09.002. Cell Metab. 2022. PMID: 36198294 Free PMC article.