Starving cancer into submission by activating BAT
- PMID: 36198290
- DOI: 10.1016/j.cmet.2022.09.009
Starving cancer into submission by activating BAT
Abstract
Activated brown adipose tissue (BAT) consumes copious amounts of circulating nutrients to fuel thermogenesis. Recently writing in Nature, Seki et al. show that this property can be leveraged to limit glucose availability for cancer cells and slow tumor growth, thereby adding cancer to the growing list of diseases that can potentially be treated by activating BAT.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Brown-fat-mediated tumour suppression by cold-altered global metabolism.Nature. 2022 Aug;608(7922):421-428. doi: 10.1038/s41586-022-05030-3. Epub 2022 Aug 3. Nature. 2022. PMID: 35922508 Free PMC article.
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