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. 2022 Oct 6;16(10):e0010657.
doi: 10.1371/journal.pntd.0010657. eCollection 2022 Oct.

Building an integrated serosurveillance platform to inform public health interventions: Insights from an experts' meeting on serum biomarkers

Kirsten E Wiens  1 , Barbara Jauregui  2 , Benjamin F Arnold  3   4 , Kathryn Banke  5 , Djibril Wade  6 , Kyla Hayford  7 , Adriana Costero-Saint Denis  8 , Robert H Hall  8 , Henrik Salje  9 , Isabel Rodriguez-Barraquer  10   11 , Andrew S Azman  1   12   13 , Guy Vernet  2   14 , Daniel T Leung  15   16 ; Collaboration on Integrated Biomarkers Surveillance
Affiliations

Building an integrated serosurveillance platform to inform public health interventions: Insights from an experts' meeting on serum biomarkers

Kirsten E Wiens et al. PLoS Negl Trop Dis. .

Abstract

The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group's insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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