Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2023 Jan;32(1):75-77.
doi: 10.1111/exd.14684. Epub 2022 Oct 20.

A randomized clinical study on the effects of emollient use on the developing infant skin microbiome and metabolome

Kimberly A Capone  1 , Diana L Friscia  1 , Janeta Nikolovski  1 , Lorena S Telofski  1 , Georgios N Stamatas  2
Affiliations
Randomized Controlled Trial

A randomized clinical study on the effects of emollient use on the developing infant skin microbiome and metabolome

Kimberly A Capone et al. Exp Dermatol. 2023 Jan.
No abstract available

PubMed Disclaimer

Conflict of interest statement

DLF and LST are employees of Johnson & Johnson Consumer Inc. KAC was an employee of Johnson & Johnson Consumer Inc. at the time the research was conducted and analysed. JN is an employee of Janssen Pharmaceutical Companies of Johnson & Johnson. GNS is an employee of Johnson & Johnson Santé Beauté France.

Figures

FIGURE 1
FIGURE 1
(A) On Day 28, the increase in microbial richness observed in the wash + lotion group was significantly greater than the increase observed in the wash‐only group (*p < 0.05). (B) Relative abundance of microflora was similar between the two groups at all points throughout the study. (C) Ceramide levels from skin surface samples statistically increased (*p < 0.05) by 56% on Day 28 compared with baseline for the wash + lotion group and remained statistically unchanged for the wash‐only group.
See this image and copyright information in PMC

References

    1. Capone KA, Dowd SE, Stamatas GN, Nikolovski J. Diversity of the human skin microbiome early in life. J Invest Dermatol. 2011;131(10):2026‐2032. - PMC - PubMed
    1. Dreno B, Araviiskaia E, Berardesca E, et al. Microbiome in healthy skin, update for dermatologists. J Eur Acad Dermatol Venereol. 2016;30(12):2038‐2047. - PMC - PubMed
    1. Kong HH, Oh J, Deming C, et al. Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis. Genome Res. 2012;22(5):850‐859. - PMC - PubMed
    1. Hon KL, Kung JSC, Ng WGG, Leung TF. Section on: emollient treatment of atopic dermatitis: latest evidence and clinical considerations. Drugs Context. 2018;7:212530. - PMC - PubMed
    1. Bouslimani A, da Silva R, Kosciolek T, et al. The impact of skin care products on skin chemistry and microbiome dynamics. BMC Biol. 2019;17(1):47. - PMC - PubMed

Publication types