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. 2022 Jul-Sep;21(3):193-197.
doi: 10.4103/aam.aam_110_20.

Enterococcal infections in a tertiary care hospital, North India

Rajesh Kumar Yadav  1 , Loveleena Agarwal  1
Affiliations

Enterococcal infections in a tertiary care hospital, North India

Rajesh Kumar Yadav et al. Ann Afr Med. 2022 Jul-Sep.

Abstract
in English, French

Background: The emergence of Enterococcus as an important nosocomial pathogen is mainly attributed to its inherent resistance to commonly used antibiotics and now in recent times, it has acquired resistance to other available therapeutic options as well.

Materials and methods: Enterococcus isolates from clinical samples received in the department of microbiology over a period of 1 year were included in the study. Isolates were identified and species determined by standard methods. Antibiotic susceptibility test was done by Kirby Bauer disc diffusion test. Epsilometer test was done to determine the minimum inhibitory concentration for vancomycin.

Results: A total of 145 Enterococcus isolates were obtained; 73 (50.3%) isolates were identified as Enterococcus faecalis, 69 (47.5%) Enterococcus faecium, 2 (1.3%) Enterococcus durans and 1 (0.68%) as Enterococcus gallinarum. Most of the isolates were from urine samples (125, 86.2%); followed by pus (16, 11.03%). Vancomycin resistance was seen in 14 (9.6%) isolates while linezolid resistance was seen in 8 (5.5%) isolates.

Conclusion: E. faecalis is the most common clinical species isolated from clinical samples and the emergence of linezolid-resistant enterococci from the hospital is a matter of concern as till now it is considered to be the last resort for treatment in patients infected with vancomycin-resistant enterococci.

Résumé Contexte: L'émergence d'Enterococcus en tant qu'agent pathogène nosocomial important est principalement attribuée à sa résistance inhérente aux antibiotiques couramment utilisés et, ces derniers temps, il a également acquis une résistance à d'autres options thérapeutiques disponibles. Matériels et Méthodes: des isolats d'entérocoques provenant d'échantillons cliniques reçus au service de microbiologie sur une période d'un an ont été inclus dans l'étude. Les isolats ont été identifiés et les espèces déterminées par des méthodes standard. Le test de sensibilité aux antibiotiques a été effectué par le test de diffusion sur disque de Kirby Bauer. Un test Epsilomètre a été effectué pour déterminer la concentration minimale inhibitrice de la vancomycine. Résultats: Au total, 145 isolats d'Enterococcus ont été obtenus ; 73 (50,3 %) isolats ont été identifiés comme Enterococcus faecalis, 69 (47,5 %) Enterococcus faecium, 2 (1,3 %) Enterococcus durans et 1 (0,68 %) comme Enterococcus gallinarum. La plupart des isolats provenaient d'échantillons d'urine (125 ; 86,2 % ); suivi de pus (16 ; 11,03 %). La résistance à la vancomycine a été observée dans 14 (9,6 %) isolats, tandis que la résistance au linézolide a été observée dans 8 (5,5 %) isolats. Conclusion: E. faecalis est l'espèce clinique la plus courante isolée à partir d'échantillons cliniques et l'émergence d'entérocoques résistants au linézolide à partir de l'hôpital est préoccupante car jusqu'à présent, elle est considérée comme le dernier recours pour le traitement des patients infectés par la vancomycine. entérocoques résistants. Mots-clés: Enterococcus faecalis, Enterococcus, entérocoques résistants au linézolide, entérocoques résistants à la vancomycine.

Keywords: Enterococcus; Enterococcus faecalis; linezolid resistant enterococci; vancomycin-resistant enterococci.

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Conflict of interest statement

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Figures

Figure 1
Figure 1
Sample wise distribution of isolates
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