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. 2022 Dec 1;36(15):2225-2227.
doi: 10.1097/QAD.0000000000003401. Epub 2022 Oct 6.

Estimated changes in price discounts for tenofovir-inclusive HIV treatments following introduction of tenofovir alafenamide

Sean Dickson  1 , Nico Gabriel  2 , Inmaculada Hernandez  2
Affiliations

Estimated changes in price discounts for tenofovir-inclusive HIV treatments following introduction of tenofovir alafenamide

Sean Dickson et al. AIDS. .

Abstract

We estimated list and net prices for tenofovir disoproxil fumarate (TDF) products Truvada, Complera, and Stribild, and their tenofovir alafenamide (TAF) versions Descovy, Odefsey, and Genvoya. Gilead offered discounts for Descovy that resulted into lower net prices compared to Truvada. This strategy encouraged patients switching from Truvada to Descovy before the availability of generic Truvada. Conversely, Gilead offered lower discounts for Odefsey and Genvoya, which resulted into higher net prices compared to Complera and Stribild.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Fig. 1
Fig. 1
Trends in list prices, Net prices and market share, 2011–2019.
See this image and copyright information in PMC

References

    1. Dickson S, Killelea A. Intentionally delayed pharmaceutical innovation under perverse incentives: Gilead's HIV pipeline as a case study. Health Aff Forefr. https://www.healthaffairs.org/do/10.1377/forefront.20210614.619677. - DOI
    1. Walensky RP, Horn T, McCann NC, Freedberg KA, Paltiel AD. Comparative pricing of branded tenofovir alafenamide-emtricitabine relative to generic tenofovir disoproxil fumarate-emtricitabine for HIV preexposure prophylaxis: a cost-effectiveness analysis. Ann Intern Med 2020; 172:583–590. - PMC - PubMed
    1. SSR Health. Available at: https://www.ssrhealth.com. [Accessed 14 June 2022]
    1. Dickson S, Gabriel N, Gellad WF, Hernandez I. Reduction in Medicaid rebates paid by pharmaceutical manufacturers for outpatient injected, inhaled, infused, implanted, or instilled drugs: the 5i loophole. J Health Polit Policy Law 2022; 10041219.doi:10.1215/03616878-10041219. [Online ahead of print]. - PubMed
    1. Hoover K, Weiming Z, Wiener J, Huang YL. Trends in truvada and descovy prescriptions for PrEP in the United States, 2014–2020. 2021. Available at: https://natap.org/2021/CROI/croi_201.htm. [Accessed 5 July 2022]

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