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. 2022:165:197-227.
doi: 10.1016/bs.irn.2022.03.003. Epub 2022 Apr 23.

Social isolation, loneliness and mental health sequelae of the Covid-19 pandemic in Parkinson's disease

Bradley McDaniels  1 , Indu Subramanian  2
Affiliations

Social isolation, loneliness and mental health sequelae of the Covid-19 pandemic in Parkinson's disease

Bradley McDaniels et al. Int Rev Neurobiol. 2022.

Abstract

People living with Parkinson Disease (PwP) have been at risk for the negative effects of loneliness even before the Coronavirus Disease 2019 (Covid-19) pandemic. Despite some similarities with previous outbreaks, the Covid-19 pandemic is significantly more wide-spread, long-lasting, and deadly, which likely means demonstrably more negative mental health issues. Although PwP are not any more likely to contract Covid-19 than those without, the indirect negative sequelae of isolation, loneliness, mental health issues, and worsening motor and non-motor features remains to be fully realized. Loneliness is not an isolated problem; the preliminary evidence indicates that loneliness associated with the Covid-19 restrictions has dramatically increased in nearly all countries around the world.

Keywords: Covid-19; Loneliness; Mental health; Parkinson disease; Social isolation.

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Figures

Fig. 1
Fig. 1
Interactions between the components of the ICF model.
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References

    1. Aarsland D., Batzu L., Halliday G.M., Geurtsen G.J., Ballard C., Ray Chaudhuri K., et al. Parkinson disease-associated cognitive impairment. Nature Reviews. Disease Primers. 2021;7(1):47. doi: 10.1038/s41572-021-00280-3. - DOI - PubMed
    1. Aarsland D., Bronnick K., Williams-Gray C., Weintraub D., Marder K., Kulisevsky J., et al. Mild cognitive impairment in Parkinson disease: A multicenter pooled analysis. Neurology. 2010;75(12):1062–1069. doi: 10.1212/WNL.0b013e3181f39d0e. - DOI - PMC - PubMed
    1. Adam E.K., Hawkley L.C., Kudielka B.M., Cacioppo J.T. Day-to-day dynamics of experience-cortisol associations in a population-based sample of older adults. Proceedings of the National Academy of Sciences. 2006;103(45):17058–17063. doi: 10.1073/pnas.0605053103. - DOI - PMC - PubMed
    1. Alschuler K.N., Roberts M.K., Herring T.E., Ehde D.M. Distress and risk perception in people living with multiple sclerosis during the early phase of the COVID-19 pandemic. Multiple Sclerosis and Related Disorders. 2021;47 doi: 10.1016/j.msard.2020.102618. - DOI - PMC - PubMed
    1. Anghelescu B.A.-M., Bruno V., Martino D., Roach P. Effects of the COVID-19 pandemic on Parkinson's disease: A single-centered qualitative study. Canadian Journal of Neurological Sciences/Journal Canadien Des Sciences Neurologiques. 2021;1–13 doi: 10.1017/cjn.2021.70. - DOI - PMC - PubMed