Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov:225:109640.
doi: 10.1016/j.buildenv.2022.109640. Epub 2022 Sep 29.

Evaluation of aerosol transmission risk during home quarantine under different operating scenarios: A pilot study

Affiliations

Evaluation of aerosol transmission risk during home quarantine under different operating scenarios: A pilot study

Toby Cheung et al. Build Environ. 2022 Nov.

Abstract

SARS-CoV-2 has been recognized to be airborne transmissible. With the large number of reported positive cases in the community, home quarantine is recommended for the infectors who are not severely ill. However, the risks of household aerosol transmission associated with the quarantine room operating methods are under-explored. We used tracer gas technique to simulate the exhaled virus laden aerosols from a patient under home quarantine situation inside a residential testbed. The Sulphur hexafluoride (SF6) concentration was measured both inside and outside the quarantine room under different operating settings including, air-conditioning and natural ventilation, presence of an exhaust fan, and the air movement generated by ceiling or pedestal fan. We calculated the outside-to-inside SF6 concentration to indicate potential exposure of occupants in the same household. In-room concentration with air-conditioning was 4 times higher than in natural ventilation settings. Exhaust fan operation substantially reduced in-room SF6 concentration and leakage rate in most of the ventilation scenarios, except for natural ventilation setting with ceiling fan. The exception is attributable to the different airflow patterns between ceiling fan (recirculates air vertically) and pedestal fan (moves air horizontally). These airflow variations also led to differences in SF6 concentration at two sampling heights (0.1 m and 1.7 m) and SF6 leakage rates when the quarantine room door was opened momentarily. Use of natural ventilation rather than air-conditioning, and operating exhaust fan when using air-conditioning are recommended to lower exposure risk for home quarantine. A more holistic experiment will be conducted to address the limitations reflected in this study.

Keywords: Aerosol transmission risk; Air conditioning; COVID-19; Fans; Home quarantine; Natural ventilation.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
(a) A snapshot of the master-bedroom; (b) a plan view diagram identifying the experimental setups both inside and outside the master-bedroom (i.e., the quarantine room). Information about in-room and hall-side samplers is highlighted in red. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2
Fig. 2
Detailed indication of experimental procedures for actions being taken, status of the test room, and exhaust fan operation schedule.
Fig. 3
Fig. 3
Time series SF6,conc under different ventilation scenarios with/without window exhaust. (a) Air-conditioning (AC) only, (b) AC with ceiling fan, (c) AC with pedestal fan, (d) Natural ventilation (NV) with ceiling fan, and (e) NV with pedestal fan. The three sampling locations are: hall-side at 0.1 m height (red line), in-room at 0.1 m height (green line), and in-room at 1.7 m height (blue line). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 4
Fig. 4
SF6,conc distribution comparison for window exhaust On and Off status at: (a) In-room sampler at 0.1 m, (b) In-room sampler at 1.7 m and (c) Hall-side sampler at 0.1 m height.
Fig. 5
Fig. 5
Plan view of the airflow patterns in air-conditioned scenarios together with the operation of (a) pedestal fan, (b) ceiling fan, and (c) window exhaust fan.
Fig. 6
Fig. 6
Schematics of the airflow pattern in naturally ventilated scenarios with windows and toilet door open: (a) plan view operating with pedestal fan, and (b) side view operating with ceiling fan.
Fig. 7
Fig. 7
Illustration diagrams of (a) a plan view and (b) a side vide for airflow generated by ceiling fan passing through the door gap (door between quarantine room and living room). The dotted blue arrows represent the turbulence incurred by the rebound airflow from the door. The grey line and arrows over the door are, respectively, indicating the air pressure gradient and the pressure direction initiated by the fans' airflow. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 8
Fig. 8
Time series outside-to-inside (master-bedroom) SF6,conc ratio. (a) AC only, (b) AC with pedestal fan, (c) AC with ceiling fan, (d) NV with pedestal fan, and (e) NV with ceiling fan.
Fig. 9
Fig. 9
Boxplot on the steady state outside-to-inside (quarantine room) SF6 concentration (i.e., O/ISF6) for the conditions with/without window exhaust under five different operating scenarios.

Similar articles

Cited by

References

    1. Bentley E.G., Kirby A., Sharma P., Kipar A., Mega D.F., Bramwell C., Penrice-Randal R., Prince T., Brown J.C., Zhou J., Screaton G.R., Barclay W.S., Owen A., Hiscox J.A., Stewart J.P., Sars-CoV-2 Omicron-B.1.1 529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe. COVID-19, 2021:2021. doi: 10.1101/2021.12.26.474085. 12.26.474085. - DOI
    1. Callaway E. What Omicron's BA.4 and BA.5 variants mean for the pandemic. Nature. 2022;606:848–849. doi: 10.1038/d41586-022-01730-y. - DOI - PubMed
    1. Christie B. Covid-19: early studies give hope omicron is milder than other variants. BMJ. 2021;375:n3144. doi: 10.1136/bmj.n3144. - DOI - PubMed
    1. Nealon J., Cowling B.J. Omicron severity: milder but not mild. Lancet. 2022;399:412–413. doi: 10.1016/S0140-6736(22)00056-3. - DOI - PMC - PubMed
    1. Sigal A. Milder disease with Omicron: is it the virus or the pre-existing immunity? Nat. Rev. Immunol. 2022;22:69–71. doi: 10.1038/s41577-022-00678-4. - DOI - PMC - PubMed