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. 2022 Sep 28:2022:7150204.
doi: 10.1155/2022/7150204. eCollection 2022.

Clinical Efficacy Analysis of Biofeedback Electrical Stimulation Combined with Doxycycline in the Treatment of Type IIIA Chronic Prostatitis

Xiaoyong Sun  1 , Tangtang Lin  1 , Jinying Fang  1 , Jinming Liu  1 , Wenliang Yao  2 , Liguo Geng  3 , Jinfeng Zhang  4
Affiliations

Clinical Efficacy Analysis of Biofeedback Electrical Stimulation Combined with Doxycycline in the Treatment of Type IIIA Chronic Prostatitis

Xiaoyong Sun et al. Evid Based Complement Alternat Med. .

Retraction in

Abstract

Purpose: To analyse the clinical efficacy of biofeedback electrical stimulation combined with doxycycline in the treatment of type IIIA chronic prostatitis.

Methods: Eighty patients who met the diagnostic criteria of type IIIA chronic prostatitis in our hospital between February 2020 and February 2022 were selected and equally divided into the drug group and electrical stimulation group according to the random number table method. The drug group was treated with medication alone for 4 weeks; the electrostimulation group was treated with biofeedback electrostimulation on top of medication for 12 weeks. The expressed prostatic secretious (EPS) routine (lecithin bodies, white blood cells) and the maximum urinary flow rate (Q max) and mean urinary flow rate (Q ave) were measured before and after treatment in both groups, and the National Institutes of Health chronic prostatitis symptom index (NIH-CPSI) was used to score the urinary symptom, pain or discomfort, and quality of life and determine the efficacy of the treatment in both groups.

Results: After treatment, the number of lecithin bodies and white blood cells in EPS improved significantly in both groups compared to before, and both the electrical stimulation group was better than the drug group (P < 0.05). After treatment, the Q max and Q ave were significantly higher in both groups than before, and both the electrical stimulation groups were higher than the drug group (P < 0.05). After treatment, the urinary symptom scores, pain or discomfort scores, quality of life scores, and total NIH-CPSI scores were significantly lower in both groups than before, and all were lower in the electrical stimulation group than in the drug group (P < 0.05). After treatment, the overall efficiency of patients in the electrical stimulation group was significantly higher than that of the drug group (P < 0.05).

Conclusion: Biofeedback electrical stimulation combined with doxycycline in the treatment of type IIIA chronic prostatitis can synergistically improve the patient's inflammation level, urinary dysfunction, relieve pelvic floor tension myalgia, and improve their quality of life, opening up new avenues for the rehabilitation of patients with type IIIA chronic prostatitis.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Comparison of the number of lecithin bodies in the EPS of the two groups. Note: (a) Number of lecithin bodies in EPS before treatment in both groups. (b) Number of lecithin bodies in EPS after treatment in both groups.
Figure 2
Figure 2
Comparison of the number of white blood cells in the EPS of the two groups. Note: (a) number of white blood cells in EPS before treatment in both groups. (b) The number of white blood cells in EPS after treatment in both groups.
Figure 3
Figure 3
Comparison of urine flow rates of the two groups. Note: (a) Qmax before and after treatment in both groups. (b) Qave before and after treatment in both groups. Compared with the same group before treatment, ∗P < 0.05; Compared with the drug group after treatment, #P < 0.05.
Figure 4
Figure 4
Comparison of NIH-CPSI scores of the two groups. Note: (a) urinary symptom scores before and after treatment in both groups. (b) Pain or discomfort scores before and after treatment in both groups. (c) Quality of life scores before and after treatment in both groups. (d) Total NIH-CPSI scores before and after treatment in both groups. Compared with the same group before treatment, ∗P < 0.05; compared with the drug group after treatment, #P < 0.05.
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