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. 2023 Mar 31;119(2):381-409.
doi: 10.1093/cvr/cvac130.

Addressing global disparities in blood pressure control: perspectives of the International Society of Hypertension

Affiliations

Addressing global disparities in blood pressure control: perspectives of the International Society of Hypertension

Aletta E Schutte et al. Cardiovasc Res. .

Abstract

Raised blood pressure (BP) is the leading cause of preventable death in the world. Yet, its global prevalence is increasing, and it remains poorly detected, treated, and controlled in both high- and low-resource settings. From the perspective of members of the International Society of Hypertension based in all regions, we reflect on the past, present, and future of hypertension care, highlighting key challenges and opportunities, which are often region-specific. We report that most countries failed to show sufficient improvements in BP control rates over the past three decades, with greater improvements mainly seen in some high-income countries, also reflected in substantial reductions in the burden of cardiovascular disease and deaths. Globally, there are significant inequities and disparities based on resources, sociodemographic environment, and race with subsequent disproportionate hypertension-related outcomes. Additional unique challenges in specific regions include conflict, wars, migration, unemployment, rapid urbanization, extremely limited funding, pollution, COVID-19-related restrictions and inequalities, obesity, and excessive salt and alcohol intake. Immediate action is needed to address suboptimal hypertension care and related disparities on a global scale. We propose a Global Hypertension Care Taskforce including multiple stakeholders and societies to identify and implement actions in reducing inequities, addressing social, commercial, and environmental determinants, and strengthening health systems implement a well-designed customized quality-of-care improvement framework.

Keywords: Awareness; Cardiovascular disease; Control; Epidemiology; Global; Hypertension; Inequity; International; Prevention; Regions; Treatment.

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Conflict of interest statement

Conflict of interest: A.E.S. received speaker honoraria from different pharmaceutical companies and device manufacturers for work unrelated to this paper; P.M.N. has received speaker honoraria from different pharmaceutical companies. K.K. reports research grants from A&D, Omron Healthcare, Fukuda Denshi, Otsuka Pharmaceutical, Otsuka Holdings, CureApp, Sanwa Kagaku Kenkyusho, Daiichi Sankyo, Taisho Pharmaceutical, Sumitomo Dainippon Pharma, Takeda Pharmaceutical, Mitsubishi Tanabe Pharma, Teijin Pharma, Boehringer-Ingelheim Japan, Pfizer Japan, Fukuda Lifetec, Bristol-Myers Squibb, Mochida Pharmaceutical, Roche Diagnostics; and Consulting fees from A&D, JIMRO, Omron Healthcare, CureApp, Kyowa Kirin, Sanwa Kagaku Kenkyusho, Terumo, Fukuda Denshi, Mochida Pharmaceutical; and Honoraria from Idorsia, Omron Healthcare, Daiichi Sankyo, Novartis Pharma, Mylan EPD; and Participation in Advisory Board of Daiichi Sankyo, Novartis Pharma, Fukuda Denshi outside the submitted work. J.-G.W. reports having received lecture and consulting fees from Novartis, Omron, Servier, and Viatris. M.P.S. has received consulting fees, and/or travel and research support from Medtronic, Abbott, Metavention, ReCor, Novartis, Servier, Pfizer, and Boehringer-Ingelheim. E.S.W.J. has received honoraria from pharmaceutical companies for work unrelated to this publication. N.R.P. has received financial support from several pharmaceutical companies which manufacture BP-lowering agents, for consultancy fees (Servier), research projects, and staff (Servier, Pfizer) and for arranging and speaking at educational meetings (AstraZeneca, Lri Therapharma, Napi, Servier, Sanofi, Eva Pharma, Pfizer, Glenmark Pharma, Alkem Lab, and Emcure India). He holds no stocks and shares in any such companies. This manuscript was handled by Guest Editor Thomas F. Lüscher

Figures

Figure 1
Figure 1
Change in absolute blood pressure control rates from 1990 to 2019 by country and sex (adapted with permission from the NCD Risk Factor Collaboration database,). Red dots (control rates 1990), black dots (control rates 2019).
Figure 2
Figure 2
Global trends in hypertension-related CVD morbidity and mortality (1990–2019). Reproduced with permission: percentage change in deaths, disability-adjusted life-years (DALYs), years lived with disability (YLDs), and years of life lost (YLLs) due to high systolic blood pressure according to the World Bank income classification of countries between 1990 and 2019.
Figure 3
Figure 3
Awareness rates of hypertension in 83 countries participating in opportunistic screening as part of the May Measurement Month campaign. Combined data for 2018 and 2019 in >2.7 million, with screenees per country ranging from 500 to 701 566. Only countries with at least 500 screenees are included.
Figure 4
Figure 4
Awareness, treatment, and control rates of MMM screenees defined as hypertensive (2018 and 2019). Percentage of screenees who were hypertensive: Sub-Saharan Africa: 26.6% of total (N = 370 395) screened. Americas: 40.8% of total (N = 449 117) screened *excluding the USA and Canada. Europe: 43.1% of total (N = 186 159) screened. Middle-East and North Africa: 28.3% of total (N = 139 908) screened. South and Central Asia: 31.3% of total (N = 864 394) screened. Asia Pacific: 34.1% of total (N = 1 001 001) screened.
Figure 5
Figure 5
The West–East divide in Europe for stroke risk. (Republished with permission from Oxford University Press on behalf of the European Society of Cardiology. Data source: Institute for Health Metric Evaluation. All rights reserved.)
Figure 6
Figure 6
Factors contributing to hypertension and cardiovascular disease in Asia (adapted and modified from Kario et al.).
Figure 7
Figure 7
Key recommendations for eliminating global inequities in hypertension care.

References

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