Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Sep 1;64(1):3-7.
doi: 10.1007/BF00443080.

Migration inhibition factor study in Histoplasma capsulatum

K L Anderson, A Y Sakaguchi

Migration inhibition factor study in Histoplasma capsulatum

K L Anderson et al. Mycopathologia. .

Abstract

Mice sublethally infected with viable Histoplasma capsulatum or immunized with merthiolate-killed yeast phase cells showed decreased mortality on subsequent challenge infection as compared to controls. Migration inhibition (MI) assays using peritoneal and spleen cells from immunized but unchallenged mice showed no parallel correlation with percent mortality. MI assay indices fluctuated without concomitant changes in resistance to challenge injection with live yeast phase cells. Viable vaccines induced greater resistance to challenge infection than killed cells, although both were comparable in sensitizing ability as measured by MI assay techniques with this mouse model.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Proc Soc Exp Biol Med. 1958 May;98(1):188-92 - PubMed
    1. J Reticuloendothel Soc. 1971 Jul;10(1):100-19 - PubMed
    1. J Infect Dis. 1971 Apr;123(4):439-45 - PubMed
    1. J Infect Dis. 1959 Jul-Aug;105(1):26-30 - PubMed
    1. J Immunol. 1968 Nov;101(5):1004-15 - PubMed

Publication types

Substances