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. 2022 Sep 21;9(10):ofac478.
doi: 10.1093/ofid/ofac478. eCollection 2022 Oct.

Invasive Bordetella pertussis Infection in Infants: A Case Report

Yang Liao  1   2 , Wei-Ran Li  1   2 , Yu Zhu  1   2 , Shuang-Hong Luo  1   2 , Qiong Liao  1   2 , Chao-Min Wan  1   2
Affiliations

Invasive Bordetella pertussis Infection in Infants: A Case Report

Yang Liao et al. Open Forum Infect Dis. .

Abstract

Infants are more likely to develop severe pertussis. We report a malignant pertussis case in a 2-month-old boy with respiratory failure, severe pneumonia, septic shock, and encephalopathy. Bordetella pertussis was detected from nasopharyngeal secretions by polymerase chain reaction, as well as both blood and cerebrospinal fluid samples via metagenomics next-generation sequencing.

Keywords: Bordetella pertussis; bacteremia; encephalopathy; pneumonia; whooping cough.

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