Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Aug 15;43(8):875-8.
doi: 10.1007/BF01951646.

Renal handling of bilirubin photoderivatives

M M Elías, E J Comin, J E Ochoa, E A Rodríguez Garay

Renal handling of bilirubin photoderivatives

M M Elías et al. Experientia. .

Abstract

The renal handling of unconjugated bilirubin in the dark and during light exposure was analyzed using an isolated rat kidney preparation. The parameters tested were pigment disappearance from the perfusion medium, pigment uptake by tissue, and its renal clearance. The results indicated that despite the fact that pigment disappearance from the medium was similar for both forms of pigment, the extraction ratio was higher for irradiated pigment than for pigment in the dark. When renal clearance of pigment was plotted vs pigment uptake of tissue, the results indicated that irradiated pigment may be more efficiently removed by the kidney. In addition, data on the rate of secretion of p-aminohippurate suggested that both pigment forms shared a common site for secretion.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. Clin Sci (Lond). 1981 Dec;61(6):765-71 - PubMed
    1. Am J Physiol. 1982 Sep;243(3):F284-92 - PubMed
    1. Pharmacol Rev. 1982 Dec;34(4):315-58 - PubMed
    1. Pediatr Res. 1984 Aug;18(8):696-700 - PubMed
    1. Lancet. 1958 May 24;1(7030):1094-7 - PubMed

Publication types