doi: 10.1007/BF01951654.
The synthesis of stereoselectively labelled porphobilinogen and its incorporation into protoporphyrin-IX
- PMID: 3622732
- DOI: 10.1007/BF01951654
Item in Clipboard
The synthesis of stereoselectively labelled porphobilinogen and its incorporation into protoporphyrin-IX
Experientia.
.
Abstract
11-(R)-2H porphobilinogen, stereospecifically labelled with deuterium in the aminomethylene group has been incorporated into protoporphyrin-IX by haemolysates of chicken erythrocytes. High field NMR spectroscopy confirms that the overall biochemical process is stereospecific, deuterium being retained at the alpha-, gamma- and delta-meso positions and lost from the beta-meso position.
Similar articles
-
[Delta-aminolevulinic acid dehydratase activity and protoporphyrin IX values in the erythrocytes of women in the early puerperium].Ginekol Pol. 1982;53(11):787-90. Ginekol Pol. 1982. PMID: 7184802 Polish. No abstract available.
-
Analyses of delta-aminolevulinic acid dehydratase activity and protoporphyrin levels in erythrocytes among three different species.J Dermatol. 1986 Oct;13(5):351-5. doi: 10.1111/j.1346-8138.1986.tb02954.x. J Dermatol. 1986. PMID: 3546439 No abstract available.
-
[Protoporphyrin IX level in erythrocytes of persons with alcoholic liver cirrhosis].Pol Tyg Lek. 1985 Jul 15;40(28):787-9. Pol Tyg Lek. 1985. PMID: 4059100 Polish. No abstract available.
-
Increased erythrocyte uroporphyrinogen-l-synthetase, delta-aminolevulinic acid dehydratase and protoporphyrin in hemolytic anemias.Am J Med. 1977 Sep;63(3):359-64. doi: 10.1016/0002-9343(77)90273-x. Am J Med. 1977. PMID: 900140 No abstract available.
-
Levels of delta-aminolevulinate dehydratase, uroporphyrinogen-I synthase, and protoporphyrin IX in erythrocytes from anemic mutant mice.Proc Natl Acad Sci U S A. 1977 Mar;74(3):1181-4. doi: 10.1073/pnas.74.3.1181. Proc Natl Acad Sci U S A. 1977. PMID: 265562 Free PMC article.
Cited by
-
Porphobilinogen deaminase and uroporphyrinogen III synthase: structure, molecular biology, and mechanism.J Bioenerg Biomembr. 1995 Apr;27(2):181-95. doi: 10.1007/BF02110033. J Bioenerg Biomembr. 1995. PMID: 7592565 Review.