Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023:2553:209-220.
doi: 10.1007/978-1-0716-2617-7_11.

Genome-Scale Modeling and Systems Metabolic Engineering of Vibrio natriegens for the Production of 1,3-Propanediol

Ye Zhang  1 , Dehua Liu  1   2   3 , Zhen Chen  4   5   6
Affiliations

Genome-Scale Modeling and Systems Metabolic Engineering of Vibrio natriegens for the Production of 1,3-Propanediol

Ye Zhang et al. Methods Mol Biol. 2023.

Abstract

The fastest-growing bacterium Vibrio natriegens is a highly promising next-generation workhorse for molecular biology and industrial biotechnology. In this work, we described the workflows for developing genome-scale metabolic models and genome-editing protocols for engineering Vibrio natriegens. A case study for metabolic engineering of Vibrio natriegens for the production of 1,3-propanediol was also presented.

Keywords: 1,3-Propanediol; Systems metabolic engineering; Vibrio natriegens.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Weinstock MT, Hesek ED, Wilson CM et al (2016) Vibrio natriegens as a fast-growing host for molecular biology. Nat Methods 13(10):849–851 - PubMed - DOI
    1. Maida I, Bosi E, Perrin E et al (2013) Draft genome sequence of the fast-growing bacterium vibrio natriegens strain DSMZ 759. Genome Announc 1(4):e00648–e00613 - PubMed - PMC - DOI
    1. Hoffart E, Grenz S, Lange J et al (2017) High substrate uptake rates empower Vibrio natriegens as production host for industrial biotechnology. Appl Environ Microbiol 83(22):e01614–e01617 - PubMed - PMC - DOI
    1. Erian AM, Freitag P, Gibisch M et al (2020) High rate 2,3-butanediol production with Vibrio natriegens. Bioresour Technol Rep 10:100408 - DOI
    1. Zhang Y, Li Z, Liu Y et al (2021) Systems metabolic engineering of Vibrio natriegens for the production of 1,3-propanediol. Metab Eng 65:52–65 - PubMed - DOI

Publication types

Supplementary concepts

LinkOut - more resources