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. 2023 Mar 4;76(5):934-937.
doi: 10.1093/cid/ciac825.

Anorectal Testing for Mpox Virus Infection in Men Who Have Sex With Men With and Without Proctitis

Eric A Meyerowitz  1 , Inessa Gendlina  1 , Vimi J Desai  1 , Robert Grossberg  1 , Singh R Nair  1 , Beendu Pujar  1 , Paul F Riska  1 , Heather B Root  1 , Justin Toro  1 , Julian A Torres  1 , Liise-Anne Pirofski  1   2 , Barry S Zingman  1
Affiliations

Anorectal Testing for Mpox Virus Infection in Men Who Have Sex With Men With and Without Proctitis

Eric A Meyerowitz et al. Clin Infect Dis. .

Abstract

We performed anorectal testing in 18 cis-gender men who have sex with men with symptoms consistent with mpox virus (MPXV) infection. We found rectal MPXV DNA in 9/9 with and 7/9 without proctitis. Future study of anorectal testing is needed and may inform the diagnosis and pathogenesis of MPXV disease.

Keywords: anorectal swab; men who have sex with men; mpox virus infection; proctitis.

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Conflict of interest statement

Potential conflicts of interest. P. F. R. reports grants or contracts from Merck, Finch, Summit, Artugen, Armata, Contrafect, and Janssen. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.