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Review
. 2022 Oct 11;107(4_Suppl):33-39.
doi: 10.4269/ajtmh.21-1305. Print 2022 Oct 11.

East Africa International Center of Excellence for Malaria Research: Impact on Malaria Policy in Uganda

Jane F Namuganga  1 , Joaniter I Nankabirwa  1   2 , Catherine Maiteki-Ssebuguzi  3 , Samuel Gonahasa  1 , Jimmy Opigo  3 , Sarah G Staedke  4 , Damian Rutazaana  3 , Chris Ebong  1 , Grant Dorsey  5 , Sheena S Tomko  6 , Timothy Kizza  1 , Henry D Mawejje  1 , Emmanuel Arinaitwe  1 , Philip J Rosenthal  5 , Moses R Kamya  1   2
Affiliations
Review

East Africa International Center of Excellence for Malaria Research: Impact on Malaria Policy in Uganda

Jane F Namuganga et al. Am J Trop Med Hyg. .

Abstract

Malaria is the leading cause of disease burden in sub-Saharan Africa. In 2010, the East Africa International Center of Excellence for Malaria Research, also known as the Program for Resistance, Immunology, Surveillance, and Modeling of Malaria (PRISM), was established to provide a comprehensive approach to malaria surveillance in Uganda. We instituted cohort studies and a robust malaria and entomological surveillance network at selected public health facilities that have provided a platform for monitoring trends in malaria morbidity and mortality, tracking the impact of malaria control interventions (indoor residual spraying of insecticide [IRS], use of long-lasting insecticidal nets [LLINs], and case management with artemisinin-based combination therapies [ACTs]), as well as monitoring of antimalarial drug and insecticide resistance. PRISM studies have informed Uganda's malaria treatment policies, guided selection of LLINs for national distribution campaigns, and revealed widespread pyrethroid resistance, which led to changes in insecticides delivered through IRS. Our continuous engagement and interaction with policy makers at the Ugandan Ministry of Health have enabled PRISM to share evidence, best practices, and lessons learned with key malaria stakeholders, participate in malaria control program reviews, and contribute to malaria policy and national guidelines. Here, we present an overview of interactions between PRISM team members and Ugandan policy makers to demonstrate how PRISM's research has influenced malaria policy and control in Uganda.

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Figures

Figure 1.
Figure 1.
Map of Uganda with locations of sites where health facility–based malaria surveillance is being conducted.
See this image and copyright information in PMC

References

    1. WHO , 2020. World Malaria Report 2021. Geneva, Switzerland: World Health Organization.
    1. Ministry of Health Republic of Uganda , 2021. Annual Health Sector Performance Report: Financial Year 2020/21.
    1. Ministry of Health Republic of Uganda , 2020. Uganda Malaria Indicator Survey 2018–19. Ministry of Health Kampala Uganda. Available at: https://dhsprogram.com/pubs/pdf/MIS34/MIS34.pdf. Accessed May 10, 2021.
    1. Yeka A et al. 2012. Malaria in Uganda: challenges to control on the long road to elimination: I. Epidemiology and current control efforts. Acta Trop 121: 184–195. - PMC - PubMed
    1. Staedke SG et al. 2020. Effect of long-lasting insecticidal nets with and without piperonyl butoxide on malaria indicators in Uganda (LLINEUP): a pragmatic, cluster-randomised trial embedded in a national LLIN distribution campaign. Lancet 395: 1292–1303. - PMC - PubMed

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