Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Feb;12(1):87-98.
doi: 10.1007/s40123-022-00590-z. Epub 2022 Oct 13.

The Incidence and Risk Factors for Dry Eye After Pediatric Strabismus Surgery

Yun Wang  1 , Xiao-Jiao Tang  1 , Qing Liu  1 , Lin Chen  2
Affiliations

The Incidence and Risk Factors for Dry Eye After Pediatric Strabismus Surgery

Yun Wang et al. Ophthalmol Ther. 2023 Feb.

Abstract

Introduction: This study aimed to investigate the incidence and risk factors for dry eye after pediatric strabismus surgery.

Methods: Children aged 5-12 years who underwent strabismus surgery were included in this single-center, prospective, cohort study. The ocular surface assessments were conducted 1 day before and 1, 4, and 8 weeks after surgery. The main outcome measures were the incidence of dry eye after strabismus surgery and associated risk factors.

Results: A total of 84 eyes (48 children) that underwent strabismus surgery were included in the study. The mean age at surgery was 7.21 years. The incidence of dry eye was 47.62% at 1 week, 10.71% at 4 weeks, 0% at 8 weeks after surgery. The preoperative tear breakup time (BUT) was lower in the dry eye group than that in the non-dry eye group (P ≤ 0.01). The univariate analysis showed that preoperative BUT was significantly associated with the incidence of dry eye after pediatric strabismus surgery (odds ratio [OR] 0.647, confidence interval [CI] 0.503-0.833, P ≤ 0.01).

Conclusions: Dry eye commonly occurs after pediatric strabismus surgery. Tear film instability is more common than deficient aqueous tear production in patients with dry eye after surgery. Children with a low preoperative BUT are more likely to develop dry eye after strabismus surgery.

Keywords: Dry eye; Pediatric; Risk factor; Strabismus surgery; Tear breakup time.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Demographics and clinical characteristics of the study population
See this image and copyright information in PMC

References

    1. Mohney BG. Common forms of childhood strabismus in an incidence cohort. Am J Ophthalmol. 2007;144(3):465–467. doi: 10.1016/j.ajo.2007.06.011. - DOI - PubMed
    1. Greenberg AE, Mohney BG, Diehl NN, Burke JP. Incidence and types of childhood esotropia: a population-based study. Ophthalmology. 2007;114(1):170–174. doi: 10.1016/j.ophtha.2006.05.072. - DOI - PubMed
    1. Chen D, Li R, Li X, et al. Prevalence, incidence and risk factors of strabismus in a Chinese population-based cohort of preschool children: the Nanjing Eye Study. Br J Ophthalmol. 2021;105(9):1203–1210. doi: 10.1136/bjophthalmol-2020-316807. - DOI - PubMed
    1. Wang Y, Zhao A, Zhang X, et al. Prevalence of strabismus among preschool children in eastern China and comparison at a 5-year interval: a population-based cross-sectional study. BMJ Open. 2021;11(10):e055112. doi: 10.1136/bmjopen-2021-055112. - DOI - PMC - PubMed
    1. Chen X, Fu Z, Yu J, et al. Prevalence of amblyopia and strabismus in Eastern China: results from screening of preschool children aged 36–72 months. Br J Ophthalmol. 2016;100(4):515–519. doi: 10.1136/bjophthalmol-2015-306999. - DOI - PubMed

LinkOut - more resources