Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Sep 29;14(19):4780.
doi: 10.3390/cancers14194780.

Review of Under-Recognized Adjunctive Therapies for Cancer

Affiliations
Review

Review of Under-Recognized Adjunctive Therapies for Cancer

Mary E Money et al. Cancers (Basel). .

Abstract

Patients and providers may not be aware that several adjunctive measures can significantly improve the quality of life, response to treatment, and possibly outcomes for cancer patients. This manuscript presents a review of practical under-recognized adjunctive therapies that are effective including exercise; stress-reduction techniques such as mindfulness, massage, yoga, Tai Chi, breathing exercises; importance of sleep quality; diet modifications such as calorie restriction at the time of chemotherapy and avoidance of high carbohydrate foods; supplements such as aspirin, green tea, turmeric, and melatonin; and repurposed prescription medications such as metformin and statins. Each recommendation should be tailored to the individual patient to assure no contraindications.

Keywords: Tai Chi; adjunctive cancer therapy; cancer; circadian rhythm effect on immunity; diet influence on cancer; exercise effect on cancer; fasting prior to chemotherapy; green tea; improved sleep effect on cancer; integrative oncology; ketogenic diet; melatonin; metformin; mindfulness; repurposed drugs for cancer treatment; statin therapy; stress reduction techniques; turmeric; yoga.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Schmitz K.H., Campbell A.M., Stuiver M.M., Pinto B.M., Schwartz A.L., Morris G.S., Ligibel J.A., Cheville A., Galvão D.A., Alfano C.M., et al. Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer. CA A Cancer J. Clin. 2019;69:468–484. doi: 10.3322/caac.21579. - DOI - PMC - PubMed
    1. Stout N.L., Baima J., Swisher A.K., Winters-Stone K.M., Welsh J. A Systematic Review of Exercise Systematic Reviews in the Cancer Literature (2005–2017) PM&R. 2017;9:S347–S384. doi: 10.1016/j.pmrj.2017.07.074. - DOI - PMC - PubMed
    1. Walcher L., Kistenmacher A.-K., Suo H., Kitte R., Dluczek S., Strauß A., Blaudszun A.-R., Yevsa T., Fricke S., Kossatz-Boehlert U. Cancer Stem Cells—Origins and Biomarkers: Perspectives for Targeted Personalized Therapies. Front. Immunol. 2020;11:1280. doi: 10.3389/fimmu.2020.01280. - DOI - PMC - PubMed
    1. Ligibel J.A., Bohlke K., May A.M., Clinton S.K., Demark-Wahnefried W., Gilchrist S.C., Irwin M.L., Late M., Mansfield S., Marshall T.F., et al. Exercise, Diet, and Weight Management During Cancer Treatment: ASCO Guideline. J. Clin. Oncol. 2022;40:2491–2507. doi: 10.1200/JCO.22.00687. - DOI - PubMed
    1. Morishita S., Hamaue Y., Fukushima T., Tanaka T., Fu J.B., Nakano J. Effect of Exercise on Mortality and Recurrence in Patients With Cancer: A Systematic Review and Meta-Analysis. Integr. Cancer Ther. 2020;19:1534735420917462. doi: 10.1177/1534735420917462. - DOI - PMC - PubMed

LinkOut - more resources