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Review
. 2022 Oct 2;11(19):5854.
doi: 10.3390/jcm11195854.

The Link between Stroke Risk and Orodental Status-A Comprehensive Review

Shahriar Shahi  1 , Mehdi Farhoudi  2 , Solmaz Maleki Dizaj  1 , Simin Sharifi  1 , Saeed Sadigh-Eteghad  2 , Khang Wen Goh  3 , Long Chiau Ming  4 , Jagjit Singh Dhaliwal  4 , Sara Salatin  2
Affiliations
Review

The Link between Stroke Risk and Orodental Status-A Comprehensive Review

Shahriar Shahi et al. J Clin Med. .

Abstract

One of the primary causes of disability and mortality in the adult population worldwide is stroke. A person's general health is significantly impacted by their oral and dental health. People who have poor oral health are more susceptible to conditions such as stroke. Stroke risk has long been linked to oral and dental conditions. The risk of stroke and its cost impact on the healthcare systems appear to be significantly reduced as a result of the decline in the incidence and prevalence of oral and dental illnesses. Hypothetically, better management of oral hygiene and dental health lead to reduced stroke risk. To the authors' best knowledge, for the first time, the potential link between dental health and stroke were cross-examined. The most typical stroke symptoms, oral and dental illnesses linked to stroke, and the role of oral healthcare professionals in stroke prevention are revealed. The potential mediating processes and subsequent long-term cognitive and functional neurological outcomes are based on the available literature. It must be noted that periodontal diseases and tooth loss are two common oral health measures. Lack of knowledge on the effects of poor oral health on systemic health together with limited access to primary medical or dental care are considered to be partially responsible for the elevated risk of stroke. Concrete evidence confirming the associations between oral inflammatory conditions and stroke in large cohort prospective studies, stratifying association between oral disease severity and stroke risk and disease effects on stroke survival will be desirable. In terms of clinical pathology, a predictive model of stroke as a function of oral health status, and biomarkers of systemic inflammation could be useful for both cardiologists and dentists.

Keywords: brain; gingivitis; infection; oral and dental health; periodontitis; stroke.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Link between oral health and general health.
Figure 2
Figure 2
Difference between ischemic and hemorrhagic stroke.
Figure 3
Figure 3
Gum disease: gingivitis and periodontitis.
See this image and copyright information in PMC

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