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. 1987 Sep;55(9):2311-3.
doi: 10.1128/iai.55.9.2311-2313.1987.

Absence of lipopolysaccharide in the Lyme disease spirochete, Borrelia burgdorferi

K Takayama, R J Rothenberg, A G Barbour

Absence of lipopolysaccharide in the Lyme disease spirochete, Borrelia burgdorferi

K Takayama et al. Infect Immun. 1987 Sep.

Abstract

We were unable to demonstrate the presence of the classic enterobacterium-type lipopolysaccharide in the cells of the Lyme disease spirochete, Borrelia burgdorferi B31. This finding was primarily based on chemical analysis and the absence of free lipid A upon mild acid hydrolysis of the appropriate cell extracts. These results do not preclude the possible existence of an unusual lipopolysaccharide-like compound(s) in B. burgdorferi.

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